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Publications ·Papers / Research

出版物・論文/研究

  • 論文
  • 出版物
  • 研究

 2023年  

Kawamura R, Harada Y, Yokose M, Hanai S, Suzuki Y, Shimizu T. Survey of Inpatient Consultations with General Internal Medicine Physicians in a Tertiary Hospital: A Retrospective Observational Study. Int J Gen Med. 2023 Apr 14;16:1295-1302. doi: 10.2147/IJGM.S408768. PMID: 37081930; PMCID: PMC10112478.

Yamashita S, Tago M, Tokushima Y, Harada Y, Suzuki Y, Aizawa Y, Miyagami T, Sano F, Sasaki Y, Komatsu F, Shimizu T, Naito T, Urita Y, Yamashita SI. Evaluation of a Previously Developed Predictive Model for Infective Endocarditis in 320 Patients Presenting with Fever at 4 Centers in Japan Between January 2018 and December 2020. Med Sci Monit. 2023 Apr 3;29:e939640. doi: 10.12659/MSM.939640. PMID: 37005715.

Hirosawa T, Ito T, Harada Y, Ikenoya K, Yokose M, Shimizu T. The utility of phonocardiograms in real-time remote cardiac auscultation using an internet-connected electronic stethoscope: Open-label randomized controlled pilot trial. DIGITAL HEALTH. 2023;9.

Hirosawa T, Harada Y, Yokose M, Sakamoto T, Kawamura R, Shimizu T. Diagnostic Accuracy of Differential-Diagnosis Lists Generated by Generative Pretrained Transformer 3 Chatbot for Clinical Vignettes with Common Chief Complaints: A Pilot Study. Int J Environ Res Public Health. 2023;20(4):3378.

Shimizu T, Lim TK. “Pivot and Cluster Strategy” in the light of Kahneman’s “Decision Hygiene” template. Diagnosis (Berl). 2023 Feb 14. doi: 10.1515/dx-2022-0129. Epub ahead of print. PMID: 36787200.

Harada Y, Otaka Y, Katsukura S, Shimizu T. Effect of contextual factors on the prevalence of diagnostic errors among patients managed by physicians of the same specialty: a single-centre retrospective observational study. BMJ Qual Saf. 2023 Jan 23:bmjqs-2022-015436. doi: 10.1136/bmjqs-2022-015436. Epub ahead of print. PMID: 36690471.

Nishizaki Y, Nagasaki K, Shikino K, Kurihara M, Shinozaki T, Kataoka K, Shimizu T, Yamamoto Y, Fukui S, Nishiguchi S, Katayama K, Kobayashi H, Tokuda Y. Relationship between COVID-19 care and burnout among postgraduate clinical residents in Japan: a nationwide cross-sectional study. BMJ Open. 2023 Jan 13;13(1):e066348.

Hamai A, Harada Y, Sogi M. Modifications visibles des muqueuses dues à une colite pseudomembraneuse chez un patient ayant une colostomie sigmoïdienne. CMAJ. 2023 Apr 24;195(16):E599-E600. French. doi: 10.1503/cmaj.221084-f. PMID: 37094868.

Kakimoto S, Harada Y, Shimizu T. Periportal halo in a patient with right atrial myxoma. QJM. 2023 Apr 24:hcad073. doi: 10.1093/qjmed/hcad073. Epub ahead of print. PMID: 37094183.

Kakimoto S, Harada Y, Shimizu T. Toxic Shock Syndrome with Breast Abscess in a Breast-Feeding Woman. J Gen Intern Med. 2023 Mar 31. doi: 10.1007/s11606-023-08174-8. Epub ahead of print. PMID: 37002456.

Kakimoto S, Harada Y, Shimizu T. A thermal imaging camera at the work office trigged the diagnosis of Takayasu arteritis. QJM. 2023 Mar 28:hcad049. doi: 10.1093/qjmed/hcad049. Epub ahead of print. PMID: 36975608.

Otaka Y, Harada Y, Kawamura R, Shimizu T. EPIPERICARDIAL FAT NECROSIS. Eur J Case Rep Intern Med. 2023 Mar 8;10(3):003823. doi: 10.12890/2023_003823. PMID: 36969525; PMCID: PMC10035614.

Kikuchi M, Harada Y, Hamai A, Takaoka S. Above the threshold time of coagulation: delayed diagnosis of acquired hemophilia A. Am J Med. 2023 Feb 23:S0002-9343(23)00102-X. doi: 10.1016/j.amjmed.2023.01.044. Epub ahead of print. PMID: 36841321.

Harada Y, Masuyama T, Yokose M, Shimizu T. Acute-on-Chronic Pattern of Isolated Upper Back Pain in a Patient With Acute Coronary Syndrome. Cureus. 2023 Feb 13;15(2):e34923.

Hamai A, Harada Y, Sogi M. Visible mucosal changes of pseudomembranous colitis in a sigmoid colostomy. CMAJ. 2023 Jan 17;195(2):E82.

Kano Y, Harada Y. Red spots on soft palate: an atypical peripheral sign of infective endocarditis. Am J Med. 2023 Jan 14:S0002-9343(23)00032-3.

Shimizu T, Harada Y. The first diagnostic excellence conference in Japan. Diagnosis (Berl). 2023 Apr 5. doi: 10.1515/dx-2023-0027. Epub ahead of print. PMID: 37014947.

 2022年  

Ito T, Hirosawa T, Harada Y, Kakimoto S, Shimizu T. Evaluation of Internet-Connected Real-Time Remote Auscultation: An Open-Label Randomized Controlled Pilot Trial. J Pers Med 2022;12.1950.

Shimizu T, Graber ML. An equation for excellence in clinical reasoning. Diagnosis (Berl). 2022 Nov 10. doi: 10.1515/dx-2022-0060. Epub ahead of print. PMID: 36351261.

Harada T, Harada Y, Hiroshige J, Shimizu T. Factors associated with delayed diagnosis of appendicitis in adults: A single-center, retrospective, observational study. PLoS One. 2022 Oct 20;17(10):e0276454.

Yokose M, Harada Y, Hanai S, Tomiyama S, Shimizu T. Outcomes of General Internal Medicine Consultations for Diagnosis from Specialists in a Tertiary Hospital: A Retrospective Observational Study. Int J Gen Med. 2022;15:7209-7217

Hirosawa T, Hayashi A, Harada Y, Shimizu T. The Clinical and Biological Manifestations in Women with Iron Deficiency Without Anemia Compared to Iron Deficiency Anemia in a General Internal Medicine Setting: A Retrospective Cohort Study. Int J Gen Med. 2022;15:6765-6773.

Tago M, Hirata R, Watari T, Shikino K, Sasaki Y, Takahashi H, Shimizu T. Future Research in General Medicine Has Diverse Topics and is Highly Promising: Opinions Based on a Questionnaire Survey. Int J Gen Med. 2022;15:6381-6386

Nagasaki K, Nishizaki Y, Shinozaki T, Shimizu T, Yamamoto Y, Shikino K, Fukui S, Nishiguchi S, Kurihara M, Kataoka K, Tokuda Y, Kobayashi H. Association between mental health and duty hours of postgraduate residents in Japan: a nationwide cross-sectional study. Sci Rep. 2022 Jun 23;12(1):10626.

Shimizu T, Graber M. How insight contributes to diagnostic excellence. Diagnosis (Berl). 2022 Jun 8. doi: 10.1515/dx-2022-0007.

Harada T, Harada Y, Morinaga K, Hirosawa T, Shimizu T. Bandemia as an Early Predictive Marker of Bacteremia: A Retrospective Cohort Study. Int J Environ Res Public Health. 2022 Feb 17;19(4):2275.

Miyagami T, Yamada T, Kanzawa Y, Kosugi S, Nagasaki K, Nagano H, Shimizu T, Fujibayashi K, Deshpande GA, Naito T. Large-Scale Observational Study on the Current Status and Challenges of General Medicine in Japan: Job Description and Required Skills. Int J Gen Med. 2022 Jan 29;15:975-984.

Shimizu T. System 2 Diagnostic Process for the Next Generation of Physicians: “Inside” and “Outside” Brain-The Interplay between Human and Machine. Diagnostics (Basel). 2022 Jan 30;12(2):356.

Kawamura R, Harada Y, Sugimoto S, Nagase Y, Katsukura S, Shimizu T. Incidence of Diagnostic Errors Among Unexpectedly Hospitalized Patients Using an Automated Medical History–Taking System With a Differential Diagnosis Generator: Retrospective Observational Study. JMIR Med Inform 2022;10(1):e35225

Harada T, Watari T, Watanuki S, Hiroshige J, Kushiro S, Miyagami T, Syusa S, Suzuki S, Hiyoshi T, Hasegawa S, Nabeshima S, Aihara H, Yamashita S, Tago M, Yoshimura F, Kunitomo K, Tsuji T, Hirose M, Tsuchida T, Shimizu T. Diagnostic error rates and associated factors for lower gastrointestinal perforation. Sci Rep. 2022 Jan 19;12(1):1028.

Akasaki Y, Takaki M, Konagaya K, Watanabe K, Shimizu T. Posterior inferior pancreaticduodenal artery aneurysm rupture due to median arcuate ligament syndrome. Am J Med Sci. 2022 Dec;364(6):e89-e90.

Kakimoto S, Harada Y, Shimizu T. Japanese Pit Viper Bite during Pregnancy. Eur J Case Rep Intern Med. 2022 Nov 15;9(11):003652.

Hanai S, Terasawa T, Iwata M. Asymptomatic entrapped denture in the hypopharynx. BMJ Case Rep. 2022 Nov 15;15(11):e248487.

Kunitomo K, Shimizu T, Tsuji T. A Common Diagnosis Delayed by Three “Wrong Footing” Anchoring Errors – it is Difficult to Remember What You Have Forgotten. Eur J Case Rep Intern Med. 2022 Nov 9;9(11):003615.

Sakamoto T, Shimizu T. Urinary tract infection due to herniation of bladder. Am J Med Sci. 2022 Sep 27;S0002-9629(22)00427-X. doi: 10.1016/j.amjms.2022.09.020.

Sakamoto T, Yamakawa T, Hirano K, Kobayashi A, Kasai M, Koizumi K, Yokoo T, Komatsumoto S, Murohisa T, Shimizu T. The systemic immune response due to cholesterol crystal embolization syndrome: a case report BMC Nephrol. 2022 Sep 19;23(1):314. doi: 10.1186/s12882-022-02939-9.

Hongo M, Harada Y, Shimizu T, Gu Y. Acute cytomegalovirus infection in a 61-yearold woman. CMAJ 2022 August 22;194:E1109-11. doi: 10.1503/cmaj.220042

Shimizu T, Takaki M, Konagaya K, Watanabe K, Akasaki Y. Posterior inferior pancreaticduodenal artery aneurysm rupture due to median arcuate ligament syndrome. Am J Med Sci. 2022 Jul 27:S0002-9629(22)00336-6.

Kunitomo K, Uemura N, Shimizu T, Hayano S, Tsuji T. Skin and soft tissue infections and bacteremia caused by Vibrio cincinnatiensis. IDCases. 2022 Jul 8;29:e01564.

Kakimoto S, Harada Y, Shimizu T. Mullerian Duct Cyst Infection. J Gen Intern Med. 2022 Jul 5. doi: 10.1007/s11606-022-07710-2.

Yokose M, Shimizu T. A Case of Delayed Diagnosis of Acute Pyelonephritis in a Horseshoe Kidney in an Elderly Patient. Dokkyo Medical Journal 1(2): 124-126, 2022.

Kano Y, Harada Y. Non-episodic angioedema associated with eosinophilia. BMJ Case Rep. 2022 Jun 24;15(6):e250037.

Kawahigashi T, Harada Y, Watari T, Harada T, Miyagami T, Shikino K, Inada H. Missed Opportunities for Diagnosing Vertebral Osteomyelitis Caused by Influential Cognitive Biases. Am J Case Rep. 2022 Jun 22;23:e936058.

Sato A, Yasui-Furukori N, Oda Y, Yang M, Suzuki Y, Shinozaki M, Shimizu T, Shimoda K. Asymptomatic syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following duloxetine treatment for pain with depression: Two case reports. Neuropsychopharmacol Rep. 2022 Jun 22. doi: 10.1002/npr2.12279.

Otaka Y, Harada Y, Shimizu T. Hypertrophic pachymeningitis in the context of the treatment of polymyalgia rheumatica. BMJ Case Rep. 2022 Jun 20;15(6):e250450.

Yoshida Y, Harada Y, Shimizu T. Costochondral gout. CMAJ. 2022 Jun 20;194(24):E845.

Otaka Y, Harada Y, Shimizu T. Case of bilateral Bell’s palsy. BMJ Case Rep. 2022 Jun 10;15(6):e250364.

Uemura S, Kunitomo K, Shimizu T, Tsuji T. Characteristic speech qualities associated with hypothyroidism. BMJ Case Rep. 2022 Mar 24;15(3):e244173

Kunitomo K, Shimizu T, Tsuji T. High point-like signal in the hippocampus. Emerg Med J. 2022 May;39(5):e3.

Kakimoto S, Harada Y, Shimizu T. Periorbital Necrotizing Fasciitis. J Gen Intern Med. 2022 Mar 18. doi: 10.1007/s11606-022-07484-7.

Sakamoto T, Asahara D. Shimizu T. Intercostal retraction with pleural effusion. Ann Intern Med: Clinical Cases. In Press 2022

Notomi K, Harada T, Watari T, Hiroshige J, Shimizu T. Misdiagnosis due to false-positive detection of pneumococcal urinary antigen: a case report. Eur J Case Rep Intern Med. 2022 Feb 14;9(2):003198

Kurihara M, Nomura Y, Katsube O, Umetsu T, Numao T, Shimizu T, Sugiyama K. The challenge of differentiating tuberculous meningitis from bacterial meningitis. Respirol Case Rep. 2022 Feb 20;10(3):e0910

Hamashoji M, Kunitomo K, Shimizu T, Tsuji T. Carbon Monoxide Poisoning in a Psychiatric Patient Mistaken for Indefinite Complaints. Eur J Case Rep Intern Med. 2022 Mar 22;9(3):003242

Kakimoto S, Harada Y, Shimizu T. Oral stings by spermatophores of a squid. QJM. 2022 Mar 22;115(3):175-176.

Amano M, Harada Y, Shimizu T. Effectual Diagnostic Approach: A New Strategy to Achieve Diagnostic Excellence in High Diagnostic Uncertainty. Int J Gen Med. 2022;15:8327-8332

Ishizuka K, Yamashita S, Katsukura S, Matsuura H. Five tips to guide beginners and young general physicians on writing clinical image reports. J Gen Fam Med. 2022 Jul 15;23(6):413-415.

Mizumoto J, Shimizu T. The remains of the D. J Gen Fam Med. 2022 May 30;23(4):228-232.

Tago M, Shikino K, Hirata R, Kunitomo K, Otaka Y, Matsui S, Shimizu T. How can we train exemplary general hospitalists?. JHGM. 2022:4-3;172-3

Shikino K, Tago M, Watari T, Sasaki Y, Takahashi H, Shimizu T. Five tips on clinical research mentorship for Japanese generalists. JHGM. 2022:4-3;170-1

 2021年  

Kawamura R, Harada Y, Shimizu T. Diagnostic Effect of Consultation Referral from Gastroenterologists to Generalists in Patients with Undiagnosed Chronic Abdominal Pain: A Retrospective Study. Healthcare 2021;9(9):1150.

Nagasaki K, Nishizaki Y, Shinozaki T, Kobayashi H, Shimizu T, Okubo T, Yamamoto Y, Konishi R, Tokuda Y. Impact of the resident duty hours on in-training examination score: A nationwide study in Japan. Med Teach. 2021 Nov 24:1-8.

Nagasaki K, Nishizaki Y, Nojima M, Shimuzu T, Konishi R, Okubo T, Yamamoto Y, Morishima R, Kobayashi H, Tokuda Y. Validation of the General Medicine In-training Examination Using the Professional and Linguistic Assessments Board Examination among Postgraduate Residents in Japan. Int J Gen Med. 2021;14:6487-6495.

Kawamura R, Harada Y, Shimizu T. Diagnostic Effect of Consultation Referral from Gastroenterologists to Generalists in Patients with Undiagnosed Chronic Abdominal Pain: A Retrospective Study. Healthcare 2021;9(9):1150.

Hirosawa T, Harada Y, Ikenoya K, Kakimoto S, Aizawa Y, Shimizu T. The Utility of Real-Time Remote Auscultation Using a Bluetooth-Connected Electronic Stethoscope: Open-Label Randomized Controlled Pilot Trial. JMIR Mhealth Uhealth 2021;9(7):e23109. doi: 10.2196/23109

Harada Y, Katsukura S, Kawamura R, Shimizu T. Effects of a Differential Diagnosis List of Artificial Intelligence on Differential Diagnoses by Physicians: An Exploratory Analysis of Data from a Randomized Controlled Study. Int J Environ Res Public Health. 2021 May 23;18(11):5562.

Shimizu T. The 6C model for accurately capturing the patient’s medical history. Diagnosis (Berl). 2021 Apr 23. doi: 10.1515/dx-2020-0126.

Miyagami T, Harada T, Watari T, Shimizu T. Evaluating Cognitive Bias from Diagnostic Error Cases Using the Cognitive Bias Codex. J Hosp Gen Med, In Press 2021.

Tago M, Watari T, Shikino K, Sasaki Y, Takahashi H, Shimizu T. A statement on the ten fascinating skills of the Japanese hospitalist. J Hosp Gen Med, In Press 2021.

Nishizaki Y, Nozawa K, Shinozaki T, Shimizu T, Okubo T, Yamamoto Y, Konishi R, Tokuda Y. Difference in the general medicine in-training examination score between community-based hospitals and university hospitals: a cross-sectional study based on 15,188 Japanese resident physicians. BMC Med Educ. 2021 Apr 15;21(1):214.

Harada Y, Katsukura S, Kawamura R, Shimizu T. Efficacy of Artificial-Intelligence-Driven Differential-Diagnosis List on the Diagnostic Accuracy of Physicians: An Open-Label Randomized Controlled Study. Int J Environ Res Public Health. 2021 Feb 21;18(4):2086.

Miyagami T, Uehara Y, Harada T, Watari T, Shimizu T, Nakamura A, Ogura N, Kushiro S, Masuyama K, Kanai Y, Yang KS, Naito T. Delayed treatment of bacteremia during the COVID-19 pandemic. Diagnosis (Berl). 2021 Jan 19:dx-2020-0114.

Hirosawa T, Harada Y, Nishinobu T, Honda Y, Morinaga K, Takase H, Shimizu T. The diagnostic value of Reversed Carnett’s sign for detecting intra-abdominal lesion in patients with acute abdominal pain. JHGM. 2021;3(1):11-20.

Nagase Y, Harada Y. Misdiagnosis of Rectus Abdominis Abscess Owing to Delayed Contrast-Enhanced Computed Tomography. Eur J Case Rep Intern Med. 2021 Dec 30;8(12):003097.

Harada T, Shimizu T. Fitz-Hugh-Curtis syndrome without salpingitis: Should contrast-enhanced computed tomography be a routine diagnostic procedure? Clin Case Rep. 2021 Dec 13;9(12):e05211.

Kawahigashi T, Shimizu T, Kawabe T, Kida Y, Watanabe K. Delayed diagnosis of pulmonary embolism. Am J Med. 2021 Dec 19:S0002-9343(21)00810-X.

Komaba W, Harada Y, Ishida Y, Tamashiro A, Tomita A. Into the duct: an unusual source of bacteremia. Am J Med. 2021 Oct 27:S0002-9343(21)00707-5.

Sota T, Ohtani, Okuno S, Yamada H, Nanjo Y, Harada Y. Isolated muscular sarcoidosis that presented as acute myopathy. JHGM. 2021;3-5:174-178.

Kakimoto S, Harada Y, Shimizu T. Acute upper airway obstruction by a goitre due to Hashimoto’s thyroiditis. BMJ Case Rep. 2021 Sep 8;14(9):e245198.

Kunitomo K, Shimizu T, Harada Y. A case of multiple ring-shaped aphthae without pseudomembranous colitis. Am J Med Sci. 2021 Aug 15:S0002-9629(21)00284-6.

Miyagami T, Takada A, Shimizu T, Naito T. Delayed diagnosis of a piriformis abscess due to hyposkillia and communication error. BMJ Case Rep. 2021 Aug 11;14(8):e242088.

Kawamura R, Suzuki Y, Harada Y, Shimizu T. Atypical presentation of colorectal carcinoma with sole multiple osteolytic bone metastases: a case report. J Med Case Rep. 2021 May 21;15(1):256.

Kawahigashi T, Shimizu T, Kawabe T, Kida Y, Watanabe K. Missed Diagnosis of Subarachnoid Haemorrhage. Eur J Case Rep Intern Med. 2021 May 31;8(5):002616.

Sakamoto T, Kaburaki M, Shimizu T. Salt-and-pepper skin appearance & Systemic sclerosis. QJM. 2021 May 6:hcab070.

Yokose M, Shimizu T. A Case of Ramsay Hunt Syndrome That Began with Vestibular Symptoms: A Great Mimicker. Am J Med. 2021 Apr;134(4):e271-e272.

Ito T, Harada Y, Shimizu T. Diagnostic and Management Errors in an Immunodeficient Patient with Pneumococcal Pneumonia with Bacteraemia due to Incorrect Assessment of the Patient’s Immune Status. Eur J Case Rep Intern Med. 2021 Apr 26;8(4):002557.

Kano Y, Harada Y. Moist lesion in the third webspace of the fingers. BMJ. 2021;373:n729.

Harada T, Sasaki Y, Tokunaga T, Yoshizawa A, Miura S, Ikeda K, Saito T, Hiroshige J. 18F-Fluorodeoxyglucose positron emission tomography computed tomography detection of single organ vasculitis of the breast: A case report. Medicine (Baltimore). 2021 Mar 26;100(12):e25259.

Harada T, Harada Y, Shimizu T. Vertebral Artery Dissection after Exposure to Levofloxacin: A Report of Two Cases. Intern Med. 2021 Mar 22. doi: 10.2169/internalmedicine.6736-20. Epub ahead of print.

Masuda M, Sakamoto T, Shimizu T. Wellens’ Syndrome. Am J Med Sci. 2021 Feb 20:S0002-9629(21)00066-5.

Kawamura R, Harada Y, Shimizu T. Missed Diagnosis of Cholangiocarcinoma Presenting with Atypical Symptoms. Eur J Case Rep Intern Med. 2021 Jan 26;8(1):002207.

Tago M, Watari T, Shikino K, Sasaki Y, Takahashi H, Shimizu T. Five Tips for Becoming an Ideal General Hospitalist. Int J Gen Med. 2021 Dec 29;14:10417-10421.

Tago M, Watari T, Shikino K, Yamashita S, Sasaki Y, Takahashi H, Shimizu T. Research trends of general hospitalists in Japan:a cross-sectional questionnaire-based personal survey. JHGM 2021;3-6:225-7.

Harada T, Miyagami T, Watari T, Kawahigashi T, Harada Y, Shikino K, Shimizu T. Barriers to diagnostic error reduction in Japan. Diagnosis (Berl). 2021 Jun 30. doi: 10.1515/dx-2021-0055. Epub ahead of print. PMID: 34187115.

Sakamoto T, Kaburaki M, Shimizu T. Nailfold capillaroscopy findings and systemic sclerosis. QJM. 2021 May 28:hcab156.

Tago M, Watari T, Shikino K, Sasaki Y, Takahashi H, Shimizu T. A statement on the ten fascinating skills of the Japanese hospitalist. J Hosp Gen Med, In Press 2021.

Shikino K, Watari T, Tago M, Sasaki Y, Takahashi H, Shimizu T. Five tips on writing case reports for Japanese generalists. J Gen Fam Med. 2021;22:111–112.

Mizumoto J, Shimizu T. Clinical Problem Solving: Unforgettable in every way. J Gen Fam Med. In Press, 2021

Mizumoto J, Shimizu T. Why‐not‐doing‐high‐tech‐test Syndrome. J Gen Fam Med. 2021;22:70–74.

 2020年  

Nishizaki Y, Shimizu T, Shinozaki T, Okubo T, Yamamoto Y, Konishi R, Tokuda Y. Impact of general medicine rotation training on the in-training examination scores of 11, 244 Japanese resident physicians: a Nationwide multi-center cross-sectional study. BMC Med Educ. 2020 Nov 13;20(1):426.

Shimizu T. Horizontal and vertical tracing: a cognitive forcing strategy to improve diagnostic accuracy. Postgrad Med J. 2020 Oct;96(1140):581-583.

Harada Y, Shimizu T. Impact of a Commercial Artificial Intelligence-Driven Patient Self-Assessment Solution on Waiting Times at General Internal Medicine Outpatient Departments: Retrospective Study. JMIR Med Inform. 2020 Aug 31;8(8):e21056.

Hirosawa T, Harada Y, Morinaga K, Takase H, Nin M, Shimizu T. Eosinopenia as a diagnostic marker of bloodstream infection in a general internal medicine setting: a cohort study. BMC Infect Dis. 2020 Jan 30;20(1):85.

Harada Y, Masuda M, Hirosawa T, Takase H, Morinaga K, Nin M, Shimizu T. Safety and efficacy of outpatient follow-up for referred patients with undiagnosed fever: A retrospective cohort study. Medicine (Baltimore). 2020 Jan;99(5):e18532.

Mizusawa K, Shimizu T. Three Cases of Food Poisoning Due to Paralepistopsis acromelalga Diagnosed from an Outbreak of Erythromelalgia. Intern Med. 2020 Dec 22.

Ito T, Sawachika H, Harada Y, Shimizu T. The Dangers of Immediately Performing a Sensitive and Specific Investigation versus the Dangers of Delaying It: A Cautionary Case of Hodgkin’s Lymphoma. Eur J Case Rep Intern Med. 2020 Dec 1;7(12):002138.

Akutagawa K, Kunitomo K, Shimizu T, Tsuji T. Organophosphate Poisoning: Vital Signs Are Not Vital In Diagnosis. QJM. 2020 Nov 27:hcaa319.

Sakamoto T, Harada Y, Shimizu T. A cat-and-mouse game? Multiple abscesses due to Staphylococcus aureus bacteremia. Am J Med. 2020 Nov 24:S0002-9343(20)31048-2.

Kano Y, Harada Y. Popliteal ecchymosis in ruptured Baker’s cyst. Am J Med. 2020 Oct 31:S0002-9343(20)30926-8.

Kuwabara R, Harada Y. Is a gallbladder coming back?: a seroma in the gallbladder fossa. Am J Med. 2020 Oct 31:S0002-9343(20)30927-X.

Harada T, Watari T, Miyagami T, Watanuki S, Shimzu T, Hiroshige J. COVID Blindness: Delayed Diagnosis of Aseptic Meningitis in the COVID-19 Era. Eur J Case Rep Intern Med. 2020 Oct 23;7(11):001940.

Harada Y, Shimizu T. Delayed Diagnosis of Pulmonary Thromboembolism Due to Overfocus on COVID-19. Eur J Case Rep Intern Med. 2020 Oct 21;7(11):002002.

Kikuchi K, Yasui-Furukori N, Yokoyama S, Hasegawa C, Kokubun A, Katsukura S, Shimizu T, Shimoda K. Clozapine-associated severe eosinophilia following lithium rebound neutropenia: A case report. Neuropsychopharmacol Rep. 2020 Sep 19.

Shimizu T. Elderly woman with swollen leg. J Am Coll Emerg Physicians Open. 2020 Sep 7;1(5):1149-1150.

Miyagami T, Harada T, Terukina H, Komori A, Watari T, Shimizu T, Naito T. Diagnostic Difficulties in Treating a Typical Case of a Patient Being a Doctor. Am J Med. 2020 Jul 10:S0002-9343(20)30551-9.

Harada Y, Kakimoto S, Shimizu T. Pazopanib-associated interstitial lung disease in a patient with renal cell carcinoma. BMJ Case Rep. 2020 Jul 8;13(7):e235177.

Shimizu T. Synchronous Bilateral Spontaneous Pneumothorax. Am J Med Sci. 2020 Jun 7:S0002-9629(20)30248-2.

Sato Y, Shinozaki M, Sasaki H, Shiinoki M, Shimizu T, Yasui-Furukori N, Shimoda K. Gluten-Related Disorder and Lactose Intolerance Concomitant With Avoidant/Restrictive Food Intake Disorder. Prim Care Companion CNS Disord. 2020 Jul 2;22(4):19l02517.

Wada T, Harada T, Ikeda K, Hiroshige J. Spontaneous spinal epidural haematoma due to polypharmacy including multiple antiplatelet agents. Postgrad Med J. 2020 Jun 23:postgradmedj-2020-137755.

Hirosawa T, Sakamoto T, Shimizu T. Gastric Anisakiasis. Am J Med Sci. 2020 Sep;360(3):318-319.

Fukuda M, Harada T, Shimizu T, Hiroshige J. Forchheimer Spots in Rubella. Intern Med. 2020 Jul 1;59(13):1673.

Hirosawa T, Shimizu T. Brachiocephalic Vein Thrombosis. Am J Med Sci. 2020 May;359(5):306-307.

Yokose M, Harada Y, Shimizu T. Behind the Leg: Cryptococcal Meningitis, Not Cellulitis. Am J Med. 2020 Mar;133(3):e81-e82.

Uehara K, Harada Y. Misdiagnosis of Liver Abscess Resulting From Misunderstood Culture Results. Am J Med. 2020 Feb;133(2):e44-e45.

Hirosawa T, Katsukura S, Shimizu T. SAPHO Syndrome. Am J Med Sci. 2020 Jan;359(1):e5-e6.

Harada T, Shimizu T, Kaji Y, Suyama Y, Matsumoto T, Kosaka C, Shimizu H, Nei T, Watanuki S. A Perspective from a Case Conference on Comparing the Diagnostic Process: Human Diagnostic Thinking vs. Artificial Intelligence (AI) Decision Support Tools. Int J Environ Res Public Health. 2020 Aug 22;17(17):6110.

Yokose M, Harada Y, Shimizu T. The Reply. Am J Med. 2020 Jun;133(6):e328.

Uehara K, Harada Y. The Reply. Am J Med. 2020 May;133(5):e211.

Terui T, Mizumoto J, Harada Y, Ohya A, Takeda Y. A report of the Social Vital Signs Workshop at WONCA Asia Pacific Regional Conference 2019. J Gen Fam Med. 2020 Feb 18;21(3):92-93.

 2019年  

Shimizu T. Reflection Of Reflections: Building Diagnostic Expertise. Int J Gen Med. 2019 Oct 7;12:363-365.

Norii T, Homma Y, Shimizu H, Takase H, Kim SH, Nagata S, Shimosato A, Crandall C; Japanese Procedural Sedation and Analgesia Registry investigators. Procedural sedation and analgesia in the emergency department in Japan: interim analysis of multicenter prospective observational study. J Anesth. 2019 Apr;33(2):238-249.

Yokoyama N, Shiraki R, Watanabe T, Shiinoki M, Nin M, Shimizu T, Yasui-Furukori N, Shimoda K. Difficult differentiation of a somatic symptom disorder from anterior cutaneous nerve entrapment syndrome (ACNES): a case report. BMC Psychiatry. 2019 Dec 12;19(1):394.

Takase H, Shimizu T. Erythema nodosum-like lesion on heel in a patient assumed Behçet’s disease. BMJ Case Rep. 2019 Nov 19;12(11):e232056.

Sakamoto T, Takase H, Shimizu T. Secretion from umbilicus. BMJ Case Rep. 2019 Aug 15;12(8):e231139.

Mitsutake A, Harada Y, Tomita A, Ueshima K. Intramural haematoma of the oesophagus. BMJ Case Rep. 2019 Jul 10;12(7):e230433.

Shimizu T, Harada Y. Preauricular Vertical Creases. Intern Med. 2019 Oct 15;58(20):3067.

Tanaka M, Harada T. Koplik spots in measles. Postgrad Med J. 2019 Aug;95(1126):454.

Notomi K, Harada T. Achenbach syndrome. CMAJ. 2019 May 27;191(21):E584.

Hirosawa T, Shiinoki M, Shimizu T. Cerebral Venous Thrombosis. Am J Med Sci. 2019 Jul;358(1):e3.

Harada Y, Hayashi M. Severe leptospirosis in a patient with positive serological test for spotted fever rickettsiosis. BMJ Case Rep. 2019 Jan 10;12(1):bcr-2018-226514.

Mizumoto J, Shimizu T. All that glitters is not gold. J Gen Fam Med. 2019 Jul 4;20(5):180-184.

Mizumoto J, Terui T, Komatsu M, Ohya A, Suzuki S, Horo S, Sugihara D, Otaka Y, Ashino A, Imura H, Harada Y, Sato K. Social vital signs for improving awareness about social determinants of health. J Gen Fam Med. 2019 May 2;20(4):164-165.

Shimizu T. Author Reply: Lumbar Kyphosis. Intern Med. 2019 Jul 1;58(13):1977.

 2018年  

Amano M, Shimizu T. Mondor’s Disease: A Review of the Literature. Intern Med. 2018 Sep 15;57(18):2607-2612.

Nishizaki Y, Shinozaki T, Kinoshita K, Shimizu T, Tokuda Y. Awareness of Diagnostic Error among Japanese Residents: a Nationwide Study. J Gen Intern Med. 2018 Apr;33(4):445-448.

Shimizu T, Nemoto T, Tokuda Y. Effectiveness of a clinical knowledge support system for reducing diagnostic errors in outpatient care in Japan: A retrospective study. Int J Med Inform. 2018 Jan;109:1-4.

Harada Y, Komori I, Morinaga K, Shimizu T. Microangiopathic haemolytic anaemia with thrombocytopenia induced by vitamin B12 deficiency long term after gastrectomy. BMJ Case Rep. 2018 Sep 19;2018:bcr2018225915.

Arai T, Kogi K, Honda Y, Suzuki T, Kawai K, Okamoto M, Fujioka T, Murata N. Lorazepam as a Cause of Drug-Induced Liver Injury. Case Rep Gastroenterol. 2018 Aug 31;12(2):546-550.

Hirosawa T, Shimizu T. Osmotic demyelination syndrome due to hyperosmolar hyperglycemia. Cleve Clin J Med. 2018 Jul;85(7):511-513.

Jinno A, Hirosawa T. Aortic intramural haematoma associated with pulmonary artery periadventitial haematoma. BMJ Case Rep. 2018 May 18;2018:bcr2018224853.

Shimizu T. Severe Hyperkyphosis. Intern Med. 2018 Aug 1;57(15):2281.

Jinno A, Hirosawa T, Shimizu T. Hepatic portal venous gas after diving. BMJ Case Rep. 2018 Jan 12;2018:bcr2017223844.

Kamijo C, Harada Y. Delayed Diagnosis of Cast Nephropathy. Am J Med. 2018 Jan;131(1):e23.

Watanuki S, Sada R, Ishikane M, Shimizu T, Kutsuna S. The Tokyo GIM Conference: Clinical reasoning conference from real cases. J Gen Fam Med. 2018 Sep 24;19(6):228.

 2017年  

Shimizu T, Nemoto T, Tokuda Y. Effectiveness of a clinical knowledge support system for reducing diagnostic errors in outpatient care in Japan: A retrospective study. Int J Med Inform. 2017:109:1-4. doi: 10.1016/j.ijmedinf.2017.09.010. Epub 2017 Sep 25.

Morinaga K, Yamanaka K. Concomitant crystal-induced and septic arthritis. IDCases. 2017 Jun 27;9:97. doi: 10.1016/j.idcr.2017.04.018. eCollection 2017.

Morinaga K, Shimizu T. Bilateral tarsal tunnel syndrome. Am J Med. 2017 Oct;130(10):e437-e438. doi: 10.1016/j.amjmed.2017.05.009. Epub 2017 Jun 8.

Shibaike Y, Hirosawa T, Shimizu T. Shell in the rectum. BMJ Case Rep. 2017 Jul 5;2017:bcr2017221125. doi: 10.1136/bcr-2017-221125.

Harada T, Hirosawa T, Morinaga K, Shimizu T. Metoclopramide-induced Serotonin Syndrome. Intern Med. 2017;56(6):737-739. doi: 10.2169/internalmedicine.56.7727.

Harada T, Suyama Y, Hiratsuka Y, Shimizu T. An Arterial Perihepatic Enhancement Caused by Spontaneous Bladder Rupture. Urology . 2017 Feb;100:e7-e8. doi: 10.1016/j.urology.2016.11.036. Epub 2016 Nov 25.

Hirose K, Hirosawa T, Shimizu T. Unilateral cutaneous congestion induced by Valsalva manoeuvre due to vascular malformation. BMJ Case Rep. 2017 Mar 9;2017:bcr2017219625. doi: 10.1136/bcr-2017-219625.

 2016年  

Hirosawa T, Shimizu T, Isegawa T, Tanabe M. Left pleural effusion caused by pancreaticopleural fistula with a pancreatic pseudocyst. BMJ Case Rep. 2016 Aug 24;2016:bcr2016217175. doi: 10.1136/bcr-2016-217175.

Mizuno A, Tsugawa Y, Shimizu T, Nishizaki Y, Okubo T, Tanoue Y, Konishi R, Shiojiri T, Tokuda Y. The Impact of the Hospital Volume on the Performance of Residents on the General Medicine In-Training Examination: A Multicenter Study in Japan. Intern Med. 2016;55(12):1553-8.doi: 10.2169/internalmedicine.55.6293. Epub 2016 Jun 15.

Harada Y. Transient T-wave change in Guillain-Barré syndrome. J Gen Fam Med. 2017 Jun 21;18(6):460-461. doi: 10.1002/jgf2.106. eCollection 2017 Dec.

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研究情報の公開について(オプトアウト)

通常、臨床研究を実施する際には、文書もしくは口頭で説明・同意を得て実施をしますが、臨床研究のうち、患者さまへの侵襲及び介入を伴わず、診療情報等の情報のみを用いた研究等については、国が定めた指針に基づき「研究対象となる患者さまのお一人ずつから文書または口頭による同意を得る必要はありません」とされています。しかし、その際は研究の目的を含めて研究の実施についての情報を公開し、さらに拒否の機会を保障することが必要とされます。このような手法を「オプトアウト」と言います。

オプトアウトを用いた臨床研究は下記の通りです。尚、研究への協力を希望されない場合は、下記文書内に記載されている各研究の担当者までお知らせください。

獨協医科大学病院 総合診療科で実施の研究一覧

研究課題名
感染性心内膜炎チーム設立に伴う感染性心内膜炎診療の変化:後ろ向き観察研究
大学病院総合診療科から他科へのコンサルテーションの内容と結果に関する横断研究
大学病院総合診療科に院内他科から紹介される患者の診断に関する横断研究
大学病院入院中に院内他科から総合診療科へ行われるコンサルテーションの内容と結果に関する横断研究
大学病院総合診療科における診断エラー検証のための後ろ向き観察研究
熱源不明の症例に対する感染性心内膜炎の予測モデルの開発:多施設後ろ向き観察研究
獨協医科大学病院における黄色ブドウ球菌菌血症に対する治療介入の質の評価と介入の要否及び方法の検討
獨協医科大学病院総合診療科の外来と入院における漢方処方の比較に関する観察研究
総合診療科の連携診療における眼病変から全身性疾患を疑う患者の診断および治療に関する観察研究
血液培養もしくは尿培養から起因菌を検出した尿路感染症の入院症例における経口抗生剤への変更に関連する因子についての後方視的研究

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