出版物・論文/研究｜獨協医科大学病院・総合診療科

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出版物・論文/研究

  • 論文
  • 出版物
  • 研究
　2025年　

【原著（英文）】

  1. Kano Y, Harada Y, Nishizawa T, Shimizu T. A scoping review of fever of unknown origin with normal serum C-reactive protein. Diagnosis (Berl). 2025 Apr 11. doi: 10.1515/dx-2024-0200. Epub ahead of print. PMID: 40211923.
  2. Shimizu T. Physicians’ prism: illuminating history with structured expertise. Diagnosis (Berl). 2025 Apr 11. doi: 10.1515/dx-2025-0003. Epub ahead of print. PMID: 40205978.
  3. Nishizawa T, Ishizuka K, Miyagami T, Kondo K, Takai S, Fukushima K, Katto D, Nishizaki Y, Shimizu T. Five Strategies for Efficient and Effective Training of Japanese Resident Physicians Under the Japanese Work Style Reform. Adv Med Educ Pract. 2025 Apr 5;16:577-581. doi: 10.2147/AMEP.S511015. PMID: 40212343; PMCID: PMC11983146.
  4. Fujikawa H, Tamune H, Nishizaki Y, Nagasaki K, Kobayashi H, Nojima M, Sekine M, Shimizu T, Yamamoto Y, Shikino K, Tokuda Y. Association between residents’ work hours and patient care ownership: a nationwide cross-sectional study in Japan. BMC Med Educ. 2025 Mar 15;25(1):385. doi: 10.1186/s12909-025-06941-1. PMID: 40089705; PMCID: PMC11909906.
  5. Fujikawa H, Tamune H, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Sekine M, Kobayashi H, Tokuda Y. Association of clinical knowledge with patient care ownership among resident physicians: a nationwide cross-sectional study in Japan. BMC Med Educ. 2025 Jan 16;25(1):77. doi: 10.1186/s12909-025-06694-x. PMID: 39825343; PMCID: PMC11740326.
  6. Miyagami T, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Nojima M, Deshpande G, Naito T, Tokuda Y. Optimal outpatient training for resident physicians’ general medicine in-training examination score: a cross-sectional study. BMC Med Educ. 2025 Jan 11;25(1):49. doi: 10.1186/s12909-025-06670-5. PMID: 39799318; PMCID: PMC11724509.

【症例報告（英文）】

  1. Sakamoto T, Hirosawa T, Shimizu T. Recurrent anemia due to mucosal prolapse syndrome. EJCRIM 2025;12:doi:10.12890/_0053202514
  2. Kunitomo K, Harada Y, Tsuji T, Shimizu T. Positive Murphy’s Sign of Fitz-Hugh-Curtis Syndrome. Cureus. 2025 Feb 4;17(2):e78521. doi: 10.7759/cureus.78521. PMID: 40062118; PMCID: PMC11888360.

【その他（英文）】

  1. Hirata R, Tago M, Takahashi H, Watari T, Shikino K, Sasaki Y, Shimizu T. A Questionnaire Study of Leadership in General Medicine: General Physicians in Japan are Facing Challenges in Education and Research [Response to Letter]. Int J Gen Med. 2025 Mar 2;18:1215-1216. doi: 10.2147/IJGM.S522557. PMID: 40051894; PMCID: PMC11884409.
  2. Shimizu T, Watanuki S, Harada Y, Kawamura R, Amano M, Isoda S, Kunitomo K, Komatsu M, Miyagami T, Ishizuka K, Kosaka S, Kurihara M. Pioneering diagnosis in Asia: advancing clinical reasoning expertise through the lens of 3M. Diagnosis (Berl). 2025 Feb 10. doi: 10.1515/dx-2024-0205. Epub ahead of print. PMID: 39916520.
　2024年　

【原著（英文）】

  1. Kunitomo K, Tsuji T, Kouzaki Y, Yoshimura F, Kubosaki J, Shimizu T. Factors affecting diagnostic difficulties in aseptic meningitis: a retrospective observational study. Diagnosis (Berl). 2024 Dec 31. doi: 10.1515/dx-2024-0183. Epub ahead of print. PMID: 40125651.
  2. Harada T, Morikawa T, Furuya H, Sato T, Kakehi M, Yamada H, Shimizu T. Use of Internet/Application-Based E-consults by General Practitioners in Japan to Resolve Patients’ Problems: A Descriptive Observational Study. Cureus. 2024 Dec 31;16(12):e76690. doi: 10.7759/cureus.76690. PMID: 39742168; PMCID: PMC11688166.
  3. Katayama K, Takada T, Nishizaki Y, Nagasaki K, Shimizu T, Yamamoto Y, Watari T, Tokuda Y, Chopra V, Ohira Y. Self-Reported Time-at-Bedside and Its Association with In-Training Examination Scores of Residents in Japan. J Gen Intern Med. 2024 Dec 19. doi: 10.1007/s11606-024-09244-1. Epub ahead of print. PMID: 39702588.
  4. Harada T, Watari T, Watanuki S, Kushiro S, Miyagami T, Syusa S, Suzuki S, Hiyoshi T, Hasegawa S, Nabeshima S, Aihara H, Yamashita S, Tago M, Yoshimura F, Kunitomo K, Tsuji T, Hirose M, Tsuchida T, Shimizu T. Preventable diagnostic errors of lower gastrointestinal perforation: a secondary analysis of a large-scale multicenter retrospective study. Int J Emerg Med. 2024 Dec 20;17(1):192. doi: 10.1186/s12245-024-00781-4. PMID: 39702011; PMCID: PMC11660691.
  5. Shikino K, Nishizaki Y, Nagasaki K, Kobayashi H, Kataoka K, Shimizu T, Tokuda Y. Residency Program Directors’ Perspectives on Overtime Duty Hours and Professional Development Time in Japan. Adv Med Educ Pract. 2024 Dec 9;15:1185-1194. doi: 10.2147/AMEP.S497272. PMID: 39679064; PMCID: PMC11645432.
  6. Shikino K, Nishizaki Y, Kataoka K, Fukui S, Yokokawa D, Shimizu T, Yamamoto Y, Nagasaki K, Kobayashi H, Tokuda Y. A novel resident physician examination using clinical simulation video to assess clinical competence in Japan: a cross-sectional study. BMC Med Educ. 2024 Nov 30;24(1):1402. doi: 10.1186/s12909-024-06395-x. PMID: 39616315; PMCID: PMC11607878.
  7. Sakamoto T, Harada Y, Shimizu T. Facilitating Trust Calibration in Artificial Intelligence-Driven Diagnostic Decision Support Systems for Determining Physicians’ Diagnostic Accuracy: Quasi-Experimental Study. JMIR Form Res. 2024 Nov 27;8:e58666. doi: 10.2196/58666. PMID: 39602469.
  8. Hirosawa T, Harada Y, Tokumasu K, Shiraishi T, Suzuki T, Shimizu T. Comparative Analysis of Diagnostic Performance: Differential Diagnosis Lists by LLaMA3 Versus LLaMA2 for Case Reports. JMIR Form Res 2024;8:e64844. DOI: 10.2196/64844. PMID: 39561356
  9. Shikino K, Nishizaki Y, Kataoka K, Nojima M, Shimizu T, Yamamoto Y, Fukui S, Nagasaki K, Yokokawa D, Kobayashi H, Tokuda Y. Association between physicians’ maldistribution and core clinical competency of resident physicians: a nationwide cross-sectional study. BMJ Open. 2024 Oct 18;14(10):e083184. doi: 10.1136/bmjopen-2023-083184. PMID: 39424384.
  10. Amano M, Harada Y, Shimizu T. Impact of disclosing a working diagnosis during simulated patient handoff presentation in the emergency department: correctness matters. Diagnosis (Berl). 2024 Oct 16. doi: 10.1515/dx-2024-0121. Epub ahead of print. PMID: 39404256.
  11. Nishiguchi S, Nishizaki Y, Hamaguchi M, Goto A, Inamori M, Shikino K, Shinozaki T, Kataoka K, Shimizu T, Yamamoto Y, Fukui S, Kobayashi H, Tokuda Y. Experience of caring for patients with COVID-19 and educational achievement among Japanese resident physicians: a nationwide survey with general medicine in-training examination. BMC Med Educ. 2024 Oct 11;24(1):1125. doi: 10.1186/s12909-024-06085-8. PMID: 39390486; PMCID: PMC11468050.
  12. Hirosawa T, Harada Y, Tokumasu K, Ito T, Suzuki T, Shimizu T. Comparative Study to Evaluate the Accuracy of Differential Diagnosis Lists Generated by Gemini Advanced, Gemini, and Bard for a Case Report Series Analysis: Cross-Sectional Study. JMIR Med Inform 2024;12:e63010
  13. Hanai S, Yokose M, Harada Y, Doi Y, Shimizu T. Current management of Staphylococcus aureus bacteremia in a Japanese university hospital. Fujita Med J. 2024 Nov;10(4):106-110. doi: 10.20407/fmj.2024-010. Epub 2024 Aug 28. PMID: 39494439; PMCID: PMC11528325.
  14. Tokumasu K, Obara H, Hirosawa T, Ogawa H, Otsuka F. Postgraduate Year Two Medical Residents’ Awareness of Personal Development as a Physician during the Management of Inpatients: A Qualitative Study. Healthcare. 2024; 12(16):1621. doi: 10.3390/healthcare12161621. PMID: 39201179; PMCID: PMC11353354.
  15. Hirosawa T, Harada Y, Mizuta K, Sakamoto T, Tokumasu K, Shimizu T. Diagnostic performance of generative artificial intelligences for a series of complex case reports. DIGITAL HEALTH. 2024;10. doi:10.1177/20552076241265215
  16. Fukui S, Shimizu T, Nishizaki Y, Shikino K, Yamamoto Y, Kobayashi H, Tokuda Y. The Utility of Wearable Cameras in Developing Examination Questions and Answers on Physical Examinations: Preliminary Study. JMIR Med Educ. 2024 Jul 19;10:e53193. doi: 10.2196/53193. PMID: 39037348; PMCID: PMC11273174.
  17. Otaka Y, Harada Y, Katsukura S, Shimizu T. Diagnostic errors and characteristics of patients seen at a general internal medicine outpatient clinic with a referral for diagnosis. Diagnosis (Berl). 2024 Jul 5;11(4):400-407. doi: 10.1515/dx-2024-0041. PMID: 38963091.
  18. Hirosawa T, Harada Y, Mizuta K, Sakamoto T, Tokumasu K, Shimizu T. Evaluating ChatGPT-4’s Accuracy in Identifying Final Diagnoses Within Differential Diagnoses Compared With Those of Physicians: Experimental Study for Diagnostic Cases. JMIR Form Res 2024;8:e59267. doi: 10.2196/59267.
  19. Harada Y, Suzuki T, Harada T, Sakamoto T, Ishizuka K, Miyagami T, Kawamura R, Kunitomo K, Nagano H, Shimizu T, Watari T. Performance evaluation of ChatGPT in detecting diagnostic errors and their contributing factors: an analysis of 545 case reports of diagnostic errors. BMJ Open Quality 2024;13:e002654.
  20. Kataoka K, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Nojima M, Nagasaki K, Fukui S, Nishiguchi S, Katayama K, Kurihara M, Ueda R, Kobayashi H, Tokuda Y. Hospital Use of a Web-Based Clinical Knowledge Support System and In-Training Examination Performance Among Postgraduate Resident Physicians in Japan: Nationwide Observational Study. JMIR Med Educ. 2024 May 30;10:e52207. doi: 10.2196/52207. PMID: 38825848; PMCID: PMC11154652.
  21. Harada Y, Sakamoto T, Sugimoto S, Shimizu T. Longitudinal Changes in Diagnostic Accuracy of a Differential Diagnosis List Developed by an AI-Based Symptom Checker: Retrospective Observational Study. JMIR Form Res. 2024 May 17;8:e53985.
  22. Hirosawa T, Harada Y, Tokumasu K, Ito T, Suzuki T, Shimizu T. Evaluating ChatGPT-4’s Diagnostic Accuracy: Impact of Visual Data Integration. JMIR Med Inform. 2024;12:e55627. Published 2024 Apr 9. doi:10.2196/55627.
  23. Shikino K, Sekine M, Nishizaki Y, Yamamoto Y, Shimizu T, Fukui S, Nagasaki K, Yokokawa D, Watari T, Kobayashi H, Tokuda Y. Distribution of internal medicine rotations among resident physicians in Japan: a nationwide, multicenter, cross-sectional study. BMC Med Educ. 2024 Mar 20;24(1):316. doi: 10.1186/s12909-024-05314-4. PMID: 38509553; PMCID: PMC10956328.
  24. Shikino K, Nishizaki Y, Fukui S, Yokokawa D, Yamamoto Y, Kobayashi H, Shimizu T, Tokuda Y. Development of a Clinical Simulation Video to Evaluate Multiple Domains of Clinical Competence: Cross-Sectional Study. JMIR Med Educ. 2024 Feb 29;10:e54401.
  25. Hirosawa T, Sakamoto T, Harada Y, Tokumasu K, Shimizu T. Clinical decision support system using a machine learning model to assist simultaneous cardiopulmonary auscultation: Open-label randomized controlled trial. DIGITAL HEALTH. 2024;10. doi:10.1177/20552076241233689
  26. Otaka Y, Harada Y, Shiroto K, Morinaga Y, Shimizu T. Early swallowing rehabilitation and promotion of total oral intake in patients with aspiration pneumonia: A retrospective study. PLoS One. 2024 Jan 19;19(1):e0296828.
  27. Otsuka Y, Ishizuka K, Harada Y, Harada T, Shikino K, Shiraishi Y, Watari T. Three Subtypes of Cutaneous Nerve Entrapment Syndrome: A Narrative Review. Intern Med. 2024 Aug 15;63(16):2231-2239. doi: 10.2169/internalmedicine.2927-23. Epub 2024 Jan 13. PMID: 38220195; PMCID: PMC11414353.

【症例報告（英文）】

  1. Kakimoto S, Harada Y, Shimizu T. Lupus vulgaris. Am J Med. 2024 Nov 29:S0002-9343(24)00781-2. doi: 10.1016/j.amjmed.2024.11.028. Epub ahead of print. PMID: 39617114.
  2. Kakimoto S, Harada Y, Shimizu T. Syphilitic paronychia. Am J Med. 2024 Nov 4:S0002-9343(24)00709-5. doi: 10.1016/j.amjmed.2024.10.018. Epub ahead of print. PMID: 39505126.
  3. Kakimoto S, Harada Y, Shimizu T. Black pleural effusion. QJM. 2024 Oct 30:hcae210. doi: 10.1093/qjmed/hcae210. Epub ahead of print. PMID: 39475438.
  4. Otaka Y, Harada Y, Olson A, Aoki T, Shimizu T. Lessons in clinical reasoning – pitfalls, myths, and pearls: a case of persistent dysphagia and patient partnership. Diagnosis (Berl). 2024 Sep 3;11(4):450-454. doi: 10.1515/dx-2024-0061. PMID: 39235977.
  5. Kawamura R, Shimizu T. Auscultatory Insights: Unmasking Atypical Fibromuscular Dysplasia in Secondary Hypertension. JHGM. July 29, 2024
  6. Yokose M, Hirosawa T, Tsunashima K, Shimizu T. A Typical Case of Atypical Disease: “Three Noes” Infective Endocarditis. Cureus. July 25, 2024. doi: 10.7759/cureus.65325. PMID: 39184702; PMCID: PMC11344238.
  7. Okumura H, Inaba S, Kawashima A, Shimizu T. Insulin Autoimmune Syndrome: A Case Report Highlighting Diagnostic Pitfalls. Cureus. 2024 Jul 9;16(7):e64130. doi: 10.7759/cureus.64130. PMID: 39119412; PMCID: PMC11307240.
  8. Yamasaki N, Mizumoto J, Shimizu T. Spinal Deformity Manifested by Urinary Tract Infection: A Case of Acute-on-Chronic Mobility Dysfunction. Cureus. 2024 Mar 4;16(3):e55475.
  9. Amano T, Nishikawa T, Oka K, Ota K, Shimizu T. How an Antimicrobial Stewardship Team Treated a Nocardia farcinica-Associated Brain Abscess: A Case Report. Cureus. 2024 Feb 21;16(2):e54605. doi: 10.7759/cureus.54605. PMID: 38523941; PMCID: PMC10958982.
  10. Takimiya R, Suzuki T, Shimizu T. Supraorbital Venous Distention in SVC Syndrome. J Gen Intern Med. 2024 May;39(6):1068. doi: 10.1007/s11606-023-08352-8. Epub 2024 Feb 12. PMID: 38347348; PMCID: PMC11074078.
  11. Kakimoto S, Harada Y, Shimizu T. Kommerell’s Diverticulum. J Gen Intern Med. 2024 May;39(7):1264-1265. doi: 10.1007/s11606-024-08672-3. Epub 2024 Feb 12. PMID: 38347347; PMCID: PMC11116348.
  12. Mizumoto J, Harada Y, Terui T, Horo S, Otaka Y, Yokota Y, Komatsu M, Takeda Y. Identifying Unmet Social Needs in a Patient Living in Isolation: A Case Report. Cureus. 2024 Jan 17;16(1):e52429.

【その他（英文）】

  1. Hirata R, Tago M, Takahashi H, Watari T, Shikino K, Sasaki Y, Shimizu T. A Questionnaire Study of Leadership in General Medicine: General Physicians in Japan are Facing Challenges in Education and Research. Int J Gen Med. 2024 Nov 23;17:5465-5470. doi: 10.2147/IJGM.S490806. PMID: 39611004; PMCID: PMC11602431.
  2. Tokushima Y, Hirata R, Yamashita S, Shikino K, Shimizu T, Tago M. Enhancing Clinical Reasoning Education: Implementing Case Conferences with Semantic Qualifiers and the Dual-Process Theory. Adv Med Educ Pract. 2024 Nov 23;15:1149-1154. doi: 10.2147/AMEP.S486420. PMID: 39610835; PMCID: PMC11602430.
  3. Hirosawa T, Suzuki T, Shiraishi T, Hayashi A, Fujii Y, Harada T, Shimizu T. Adapting Artificial Intelligence Concepts to Enhance Clinical Decision-Making: A Hybrid Intelligence Framework. Int J Gen Med. 2024;17:5417-5422. doi: 10.2147/IJGM.S497753. PMID: 39582919; PMCID: PMC11585294.
  4. Hirata R, Tago M, Shikino K, Watari T, Takahashi H, Sasaki Y, Shimizu T. Precise Classification of Generalists is Necessary to Establish Evidence in General Medicine [Response to Letter]. Int J Gen Med. 2024 Aug 21;17:3625-3626. doi: 10.2147/IJGM.S490633. PMID: 39189007; PMCID: PMC11345458.
  5. Hirata R, Tago M, Shikino K, Watari T, Takahashi H, Sasaki Y, Shimizu T. Standardizing Generalist Definitions to Improve Evidence in General Medicine: Addressing Diverse Interpretations and Lack of Consistency. Int J Gen Med. 2024 Jul 3;17:2939-2943. doi: 10.2147/IJGM.S468755. PMID: 38978711; PMCID: PMC11228072.
  6. Hirosawa T, Shimizu T. The potential, limitations, and future of diagnostics enhanced by generative artificial intelligence. Diagnosis. 2024. https://doi.org/10.1515/dx-2024-0095
  7. Hirosawa, T., Shimizu, T. Enhancing English Presentation Skills with Generative Artificial Intelligence: A Guide for Non-native Researchers. Med.Sci.Educ. 2024 May 28;34(5):1179-1184. doi: 10.1007/s40670-024-02078-w. PMID: 39450042; PMCID: PMC11496412.
  8. Harada Y, Kawamura R, Yokose M, Shimizu T, Singh H. Definitions and Measurements for Atypical Presentations at Risk for Diagnostic Errors in Internal Medicine: Protocol for a Scoping Review. JMIR Res Protoc. 2024 Mar 25;13:e56933. doi: 10.2196/56933. PMID: 38526541.
  9. Mizuta K, Hirosawa T, Harada Y, Shimizu T. “Can ChatGPT-4 evaluate whether a differential diagnosis list contains the correct diagnosis as accurately as a physician?” Diagnosis, 2024. https://doi.org/10.1515/dx-2024-0027
  10. Tago M, Hirata R, Takahashi H, Yamashita S, Nogi M, Shikino K, Sasaki Y, Watari T, Shimizu T. How Do We Establish the Utility and Evidence of General Medicine in Japan? Int J Gen Med. 2024 Feb 22;17:635-638.
  11. Isoda S, Shimizu T, T. FRAMED: a framework facilitating insight problem solving. Diagnosis (Berl). 2024 Feb 23;11(3):240-243. doi: 10.1515/dx-2023-0152. PMID: 38386688.
　2023年　

【原著（英文）】

  1. Harada Y, Otaka Y, Katsukura S, Shimizu T. Prevalence of atypical presentations among outpatients and associations with diagnostic error. Diagnosis (Berl). 2023 Dec 8;11(1):40-48. doi: 10.1515/dx-2023-0060. PMID: 38059495.
  2. Watari T, Takagi S, Sakaguchi K, Nishizaki Y, Shimizu T, Yamamoto Y, Tokuda Y. Performance Comparison of ChatGPT-4 and Japanese Medical Residents in the General Medicine In-Training Examination: Comparison Study. JMIR Med Educ. 2023 Dec 6;9:e52202.
  3. Hirosawa T, Kawamura R, Harada Y, Mizuta K, Tokumasu K, Kaji Y, Suzuki T, Shimizu T. ChatGPT-Generated Differential Diagnosis Lists for Complex Case-Derived Clinical Vignettes: Diagnostic Accuracy Evaluation. JMIR Med Inform. 2023 Oct 9;11:e48808
  4. Hirosawa T, Mizuta K, Harada Y, Shimizu T. Comparative Evaluation of Diagnostic Accuracy Between Google Bard and Physicians. Am J Med. 2023 Nov;136(11):1119-1123.e18.
  5. Tago M, Hirata R, Katsuki NE, Otsuka Y, Shimizu T, Sasaki Y, Shikino K, Watari T, Takahashi H, Une K, Naito T, Otsuka F, Thompson R, Tazuma S. Contributions of Japanese Hospitalists During the COVID-19 Pandemic and the Need for Infectious Disease Crisis Management Education for Hospitalists: An Online Cross-Sectional Study. Risk Manag Healthc Policy. 2023 Aug 21;16:1645-1651.
  6. Shimizu T, Dror IE. History information management strategy for minimising biases and noise for improved medical diagnosis. BMJ Open Qual. 2023 Aug;12(3):e002367.
  7. Harada Y, Watari T, Nagano H, Suzuki T, Kunitomo K, Miyagami T, Aita T, Ishizuka K, Maebashi M, Harada T, Sakamoto T, Tomiyama S, Shimizu T. Diagnostic errors in uncommon conditions: a systematic review of case reports of diagnostic errors. Diagnosis (Berl). 2023 Aug 10;10(4):329-336.
  8. Harada Y, Tomiyama S, Sakamoto T, Sugimoto S, Kawamura R, Yokose M, Hayashi A, Shimizu T. Effects of Combinational Use of Additional Differential Diagnostic Generators on the Diagnostic Accuracy of the Differential Diagnosis List Developed by an Artificial Intelligence-Driven Automated History-Taking System: Pilot Cross-Sectional Study. JMIR Form Res. 2023 Aug 2;7:e49034.
  9. Fukui S, Shikino K, Nishizaki Y, Shimizu T, Yamamoto Y, Kobayashi H, Tokuda Y. Association between regional quota program in medical schools and practical clinical competency based on General Medicine In-Training Examination score: a nationwide cross-sectional study of resident physicians in Japan. Postgrad Med J. 2023 Oct 19;99(1177):1197-1204.
  10. Miyagami T, Shimizu T, Kosugi S, Kanzawa Y, Nagasaki K, Nagano H, Yamada T, Fujibayashi K, Deshpande GA, Flora Kisuule, Tazuma S, Naito T. Roles considered important for hospitalist and non-hospitalist generalist practice in Japan: a survey study. BMC Prim Care. 2023 Jul 7;24(1):139.
  11. Shikino K, Tago M, Hirata R, Watari T, Sasaki Y, Takahashi H, Shimizu T. Educational strategies for general medicine education in accordance with the model core curriculum for medical education in Japan. J Gen Fam Med. 2023 Apr 1;24(4):272-273.
  12. Hirosawa T, Sakamoto T, Hanai S, Harada Y, Shimizu T. Effect of Prior Antibiotic Treatment on Blood Culture in an Outpatient Department of General Internal Medicine: A Retrospective Case–Control Analysis. Int J Gen Med. 2023;16:2709-2717.
  13. Watari T, Nishizaki Y, Houchens N, Kataoka K, Sakaguchi K, Shiraishi Y, Shimizu T, Yamamoto Y, Tokuda Y. Medical resident’s pursuing specialty and differences in clinical proficiency among medical residents in Japan: a nationwide cross-sectional study. BMC Med Educ. 2023 Jun 22;23(1):464.
  14. Tago M, Hirata R, Shikino K, Watari T, Sasaki Y, Takahashi H, Shimizu T. The Milestones of Clinical Research for Young Generalist Physicians: Conducting and Publishing Studies. Int J Gen Med. 2023 Jun 12;16:2373-2381.
  15. Nagasaki K, Nishizaki Y, Shinozaki T, Shimizu T, Yamamoto Y, Shikino K, Fukui S, Nishiguchi S, Kurihara M, Katayama K, Kobayashi H, Tokuda Y. Association between prolonged weekly duty hours and self-study time among residents: a cross-sectional study. Postgrad Med J. 2023 Sep 21;99(1176):1080-1087.
  16. Shimizu T. DECLARE: A Comprehensive, Multifaceted Cognitive Forcing Strategy to Confront Complex Cases. Int J Gen Med. 2023 Apr 25;16:1505-1511.
  17. Kawamura R, Harada Y, Yokose M, Hanai S, Suzuki Y, Shimizu T. Survey of Inpatient Consultations with General Internal Medicine Physicians in a Tertiary Hospital: A Retrospective Observational Study. Int J Gen Med. 2023 Apr 14;16:1295-1302.
  18. Yamashita S, Tago M, Tokushima Y, Harada Y, Suzuki Y, Aizawa Y, Miyagami T, Sano F, Sasaki Y, Komatsu F, Shimizu T, Naito T, Urita Y, Yamashita SI. Evaluation of a Previously Developed Predictive Model for Infective Endocarditis in 320 Patients Presenting with Fever at 4 Centers in Japan Between January 2018 and December 2020. Med Sci Monit. 2023 Apr 3;29:e939640.
  19. Hirosawa T, Ito T, Harada Y, Ikenoya K, Yokose M, Shimizu T. The utility of phonocardiograms in real-time remote cardiac auscultation using an internet-connected electronic stethoscope: Open-label randomized controlled pilot trial. Digit Health. 2023 Mar 5;9:20552076231161945.
  20. Hirosawa T, Harada Y, Yokose M, Sakamoto T, Kawamura R, Shimizu T. Diagnostic Accuracy of Differential-Diagnosis Lists Generated by Generative Pretrained Transformer 3 Chatbot for Clinical Vignettes with Common Chief Complaints: A Pilot Study. Int J Environ Res Public Health. 2023;20(4):3378.
  21. Shimizu T, Lim TK. “Pivot and Cluster Strategy” in the light of Kahneman’s “Decision Hygiene” template. Diagnosis (Berl). 2023 Feb 14;10(3):215-217.
  22. Harada Y, Otaka Y, Katsukura S, Shimizu T. Effect of contextual factors on the prevalence of diagnostic errors among patients managed by physicians of the same specialty: a single-centre retrospective observational study. BMJ Qual Saf. 2024 May 17;33(6):386-394. doi: 10.1136/bmjqs-2022-015436. PMID: 36690471.
  23. Nishizaki Y, Nagasaki K, Shikino K, Kurihara M, Shinozaki T, Kataoka K, Shimizu T, Yamamoto Y, Fukui S, Nishiguchi S, Katayama K, Kobayashi H, Tokuda Y. Relationship between COVID-19 care and burnout among postgraduate clinical residents in Japan: a nationwide cross-sectional study. BMJ Open. 2023 Jan 13;13(1):e066348.

【症例報告（英文）】

  1. Fukushima T, Hamai A, Harada Y. Bright red ear. Emerg Med J. 2023 Dec 22;41(1):41-50.
  2. Toyoshima T, Harada Y, Morikawa T, Shimizu T. Dapsone-induced Heinz-body haemolytic anaemia. BMJ Case Rep. 2023 Oct 6;16(10):e256775.
  3. Otaka Y, Harada Y, Sugawara N, Shimizu T, Yasui-Furukori N. Relationship Between Diabetic Chorea and Timing of MRI Findings: A Systematic Review with Case Reports. Int J Gen Med. 2023 Oct 2;16:4465-4476.
  4. Hamai A, Harada Y. Masked tinea. Cleve Clin J Med. 2023 Oct 2;90(10):601-602.
  5. Yokose M, Hirosawa T, Shimizu T. A case report of Pustulotic arthro-osteitis in a middle-aged woman. JHGM. 2023: 5(5);212-214
  6. Kakimoto S, Harada Y, Shimizu T. Phlegmonous gastritis. CMAJ. 2023 Sep 11;195(35):E1181.
  7. Sakamoto T, Shimizu T. A Case of Pontine Infarction Diagnosed from Bilateral Cheiro-Oral Syndrome and Truncal Ataxia. JHGM. 2023: 5(4);168-170
  8. Hongo M, Harada Y, Shimizu T. Nontyphoidal Salmonella urinary tract infection in a young man. JHGM. 2023: 5(4);166-167
  9. Aoyama S, Yamashita S, Ishizuka K, Katsukura S, Matsuura H, Kato M. Difficulty in diagnosing peritonitis caused by multidrug-resistant tuberculosis. Clin Case Rep. 2023 Aug 29;11(9):e7759.
  10. Komoda J, Hori T, Sato K, Kusajima K, Shimizu T. Hypomagnesemia because of nedaplatin for cervical cancer: A case report. J Gen Fam Med. 2023 Jun 2;24(4):257-260.
  11. Tomiyama S, Harada Y, Shimizu T. Why not re-evaluate? The value of chest radiography. Emerg Med J. 2023 Jul;40(7):473-492.
  12. Tanaka I, Shimizu T. Unexplained hypercapnia? What a chest X-ray tells us. Am J Med Sci. 2023 Nov;366(5):e88-e89.
  13. Kakimoto S, Harada Y, Shimizu T. Gastric syphilis. QJM. 2023 Oct 6;116(9):800-801.
  14. Kojo K, Morikawa T, Kikawa T, Sasaki K, Suyama Y, Shimizu T. Diagnostic dilemma of syncope: Esophageal hiatal hernia and high-risk bundle-branch block. Intern Med. 2024 Jan 1;63(1):83-86. doi: 10.2169/internalmedicine.1569-23. Epub 2023 May 17. PMID: 37197958; PMCID: PMC10824654.
  15. Hamai A, Harada Y, Sogi M. Modifications visibles des muqueuses dues à une colite pseudomembraneuse chez un patient ayant une colostomie sigmoïdienne. CMAJ. 2023 Apr 24;195(16):E599-E600.
  16. Kakimoto S, Harada Y, Shimizu T. Periportal halo in a patient with right atrial myxoma. QJM. 2023 Sep 12;116(8):710-711.
  17. Kakura K, Harada Y, Shimizu T. A Combination of Three Nerve Entrapment Syndromes, Which was Difficult to Differentiate from a Vertebral Compression Fracture. Eur J Case Rep Intern Med. 2023 Apr 13;10(5):003863.
  18. Kakimoto S, Harada Y, Shimizu T. Toxic Shock Syndrome with Breast Abscess in a Breast-Feeding Woman. J Gen Intern Med. 2023 Jun;38(8):1994-1995.
  19. Kakimoto S, Harada Y, Shimizu T. A thermal imaging camera at the work office trigged the diagnosis of Takayasu arteritis. QJM. 2023 Jul 28;116(7):542-543.
  20. Otaka Y, Harada Y, Kawamura R, Shimizu T. EPIPERICARDIAL FAT NECROSIS. Eur J Case Rep Intern Med. 2023 Mar 8;10(3):003823.
  21. Kikuchi M, Harada Y, Hamai A, Takaoka S. Above the threshold time of coagulation: delayed diagnosis of acquired hemophilia A. Am J Med. 2023 Jun;136(6):555-557.
  22. Harada Y, Masuyama T, Yokose M, Shimizu T. Acute-on-Chronic Pattern of Isolated Upper Back Pain in a Patient With Acute Coronary Syndrome. Cureus. 2023 Feb 13;15(2):e34923.
  23. Hamai A, Harada Y, Sogi M. Visible mucosal changes of pseudomembranous colitis in a sigmoid colostomy. CMAJ. 2023 Jan 17;195(2):E82.
  24. Kano Y, Harada Y. Red spots on soft palate: an atypical peripheral sign of infective endocarditis. Am J Med. 2023 May;136(5):e92-e93.

【その他（英文）】

  1. Yokose M, Harada Y, Shimizu T. Visualizing diagnostic “hotspots” in a tertiary hospital. Eur J Intern Med. 2024 Feb;120:136-138.
  2. Hirosawa T, Shimizu T. Enhancing clinical reasoning with Chat Generative Pre-trained Transformer: a practical guide. Diagnosis (Berl). vol. 11, no. 1, 2024, pp. 102-105. doi: 10.1515/dx-2023-0116. PMID: 37779351.
  3. Shimizu T, Harada Y. The first diagnostic excellence conference in Japan. Diagnosis (Berl). 2023 Apr 5;10(4):353-355.
  4. Tago M, Hirata R, Shikino K, Watari T, Sasaki Y, Takahashi H, Katsukura S, Watanuki S, Kondo K, Shimizu T. Teaching general hospitalists appropriate leadership skills and helping them acquire these skills for use in diverse settings. JHGM 2023;5(2):35-36.
　2022年

【原著（英文）】

  1. Ito T, Hirosawa T, Harada Y, Kakimoto S, Shimizu T. Evaluation of Internet-Connected Real-Time Remote Auscultation: An Open-Label Randomized Controlled Pilot Trial. J Pers Med 2022;12.1950.
  2. Shimizu T, Graber ML. An equation for excellence in clinical reasoning. Diagnosis (Berl). 2022 Nov 10;10(2):61-63.
  3. Harada T, Harada Y, Hiroshige J, Shimizu T. Factors associated with delayed diagnosis of appendicitis in adults: A single-center, retrospective, observational study. PLoS One. 2022 Oct 20;17(10):e0276454.
  4. Yokose M, Harada Y, Hanai S, Tomiyama S, Shimizu T. Outcomes of General Internal Medicine Consultations for Diagnosis from Specialists in a Tertiary Hospital: A Retrospective Observational Study. Int J Gen Med. 2022;15:7209-7217
  5. Hirosawa T, Hayashi A, Harada Y, Shimizu T. The Clinical and Biological Manifestations in Women with Iron Deficiency Without Anemia Compared to Iron Deficiency Anemia in a General Internal Medicine Setting: A Retrospective Cohort Study. Int J Gen Med. 2022;15:6765-6773.
    https://doi.org/10.2147/IJGM.S376405
  6. Tago M, Hirata R, Watari T, Shikino K, Sasaki Y, Takahashi H, Shimizu T. Future Research in General Medicine Has Diverse Topics and is Highly Promising: Opinions Based on a Questionnaire Survey. Int J Gen Med. 2022;15:6381-6386
  7. Nagasaki K, Nishizaki Y, Shinozaki T, Shimizu T, Yamamoto Y, Shikino K, Fukui S, Nishiguchi S, Kurihara M, Kataoka K, Tokuda Y, Kobayashi H. Association between mental health and duty hours of postgraduate residents in Japan: a nationwide cross-sectional study. Sci Rep. 2022 Jun 23;12(1):10626.
  8. Shimizu T, Graber M. How insight contributes to diagnostic excellence. Diagnosis (Berl). 2022 Jun 8;9(3):311-315.
  9. Harada T, Harada Y, Morinaga K, Hirosawa T, Shimizu T. Bandemia as an Early Predictive Marker of Bacteremia: A Retrospective Cohort Study. Int J Environ Res Public Health. 2022 Feb 17;19(4):2275.
  10. Miyagami T, Yamada T, Kanzawa Y, Kosugi S, Nagasaki K, Nagano H, Shimizu T, Fujibayashi K, Deshpande GA, Naito T. Large-Scale Observational Study on the Current Status and Challenges of General Medicine in Japan: Job Description and Required Skills. Int J Gen Med. 2022 Jan 29;15:975-984.
  11. Shimizu T. System 2 Diagnostic Process for the Next Generation of Physicians: “Inside” and “Outside” Brain-The Interplay between Human and Machine. Diagnostics (Basel). 2022 Jan 30;12(2):356.
  12. Kawamura R, Harada Y, Sugimoto S, Nagase Y, Katsukura S, Shimizu T. Incidence of Diagnostic Errors Among Unexpectedly Hospitalized Patients Using an Automated Medical History–Taking System With a Differential Diagnosis Generator: Retrospective Observational Study. JMIR Med Inform 2022;10(1):e35225
  13. Harada T, Watari T, Watanuki S, Hiroshige J, Kushiro S, Miyagami T, Syusa S, Suzuki S, Hiyoshi T, Hasegawa S, Nabeshima S, Aihara H, Yamashita S, Tago M, Yoshimura F, Kunitomo K, Tsuji T, Hirose M, Tsuchida T, Shimizu T. Diagnostic error rates and associated factors for lower gastrointestinal perforation. Sci Rep. 2022 Jan 19;12(1):1028.

 

【症例報告（英文）】

  1. Akasaki Y, Takaki M, Konagaya K, Watanabe K, Shimizu T. Posterior inferior pancreaticduodenal artery aneurysm rupture due to median arcuate ligament syndrome. Am J Med Sci. 2022 Dec;364(6):e89-e90.
  2. Kakimoto S, Harada Y, Shimizu T. Japanese Pit Viper Bite during Pregnancy. Eur J Case Rep Intern Med. 2022 Nov 15;9(11):003652.
  3. Hanai S, Terasawa T, Iwata M. Asymptomatic entrapped denture in the hypopharynx. BMJ Case Rep. 2022 Nov 15;15(11):e248487.
  4. Kunitomo K, Shimizu T, Tsuji T. A Common Diagnosis Delayed by Three “Wrong Footing” Anchoring Errors – it is Difficult to Remember What You Have Forgotten. Eur J Case Rep Intern Med. 2022 Nov 9;9(11):003615.
  5. Sakamoto T, Shimizu T. Urinary tract infection due to herniation of bladder. Am J Med Sci. 2023 Apr;365(4):e51-e52.
  6. Sakamoto T, Yamakawa T, Hirano K, Kobayashi A, Kasai M, Koizumi K, Yokoo T, Komatsumoto S, Murohisa T, Shimizu T. The systemic immune response due to cholesterol crystal embolization syndrome: a case report BMC Nephrol. 2022 Sep 19;23(1):314.
  7. Hongo M, Harada Y, Shimizu T, Gu Y. Acute cytomegalovirus infection in a 61-yearold woman. CMAJ 2022 August 22;194:E1109-11.
  8. Shimizu T, Takaki M, Konagaya K, Watanabe K, Akasaki Y. Posterior inferior pancreaticduodenal artery aneurysm rupture due to median arcuate ligament syndrome. Am J Med Sci. 2022 Dec;364(6):e89-e90.
  9. Kunitomo K, Uemura N, Shimizu T, Hayano S, Tsuji T. Skin and soft tissue infections and bacteremia caused by Vibrio cincinnatiensis. IDCases. 2022 Jul 8;29:e01564.
  10. Kakimoto S, Harada Y, Shimizu T. Mullerian Duct Cyst Infection. J Gen Intern Med. 2022 Oct;37(13):3487-3488.
  11. Yokose M, Shimizu T. A Case of Delayed Diagnosis of Acute Pyelonephritis in a Horseshoe Kidney in an Elderly Patient. Dokkyo Medical Journal 1(2): 124-126, 2022.
  12. Kano Y, Harada Y. Non-episodic angioedema associated with eosinophilia. BMJ Case Rep. 2022 Jun 24;15(6):e250037.
  13. Kawahigashi T, Harada Y, Watari T, Harada T, Miyagami T, Shikino K, Inada H. Missed Opportunities for Diagnosing Vertebral Osteomyelitis Caused by Influential Cognitive Biases. Am J Case Rep. 2022 Jun 22;23:e936058.
  14. Sato A, Yasui-Furukori N, Oda Y, Yang M, Suzuki Y, Shinozaki M, Shimizu T, Shimoda K. Asymptomatic syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following duloxetine treatment for pain with depression: Two case reports. Neuropsychopharmacol Rep. 2022 Sep;42(3):387-390.
  15. Otaka Y, Harada Y, Shimizu T. Hypertrophic pachymeningitis in the context of the treatment of polymyalgia rheumatica. BMJ Case Rep. 2022 Jun 20;15(6):e250450.
  16. Yoshida Y, Harada Y, Shimizu T. Costochondral gout. CMAJ. 2022 Jun 20;194(24):E845.
  17. Otaka Y, Harada Y, Shimizu T. Case of bilateral Bell’s palsy. BMJ Case Rep. 2022 Jun 10;15(6):e250364.
  18. Uemura S, Kunitomo K, Shimizu T, Tsuji T. Characteristic speech qualities associated with hypothyroidism. BMJ Case Rep. 2022 Mar 24;15(3):e244173
  19. Kunitomo K, Shimizu T, Tsuji T. High point-like signal in the hippocampus. Emerg Med J. 2022 May;39(5):e3.
  20. Kakimoto S, Harada Y, Shimizu T. Periorbital Necrotizing Fasciitis. J Gen Intern Med. 2022 Jun;37(8):2086-2087.
  21. Sakamoto T, Asahara D. Shimizu T. Intercostal retraction with pleural effusion. Ann Intern Med: Clinical Cases. https://doi.org/10.7326/aimcc.2022.0001
  22. Notomi K, Harada T, Watari T, Hiroshige J, Shimizu T. Misdiagnosis due to false-positive detection of pneumococcal urinary antigen: a case report. Eur J Case Rep Intern Med. 2022 Feb 14;9(2):003198
  23. Kurihara M, Nomura Y, Katsube O, Umetsu T, Numao T, Shimizu T, Sugiyama K. The challenge of differentiating tuberculous meningitis from bacterial meningitis. Respirol Case Rep. 2022 Feb 20;10(3):e0910
  24. Hamashoji M, Kunitomo K, Shimizu T, Tsuji T. Carbon Monoxide Poisoning in a Psychiatric Patient Mistaken for Indefinite Complaints. Eur J Case Rep Intern Med. 2022 Mar 22;9(3):003242
  25. Kakimoto S, Harada Y, Shimizu T. Oral stings by spermatophores of a squid. QJM. 2022 Mar 22;115(3):175-176.

 

【その他（英文）】

  1. Amano M, Harada Y, Shimizu T. Effectual Diagnostic Approach: A New Strategy to Achieve Diagnostic Excellence in High Diagnostic Uncertainty. Int J Gen Med. 2022;15:8327-8332
  2. Ishizuka K, Yamashita S, Katsukura S, Matsuura H. Five tips to guide beginners and young general physicians on writing clinical image reports. J Gen Fam Med. 2022 Jul 15;23(6):413-415.
  3. Mizumoto J, Shimizu T. The remains of the D. J Gen Fam Med. 2022 May 30;23(4):228-232.
  4. Tago M, Shikino K, Hirata R, Kunitomo K, Otaka Y, Matsui S, Shimizu T. How can we train exemplary general hospitalists?. JHGM. 2022：4-3;172-3
  5. Shikino K, Tago M, Watari T, Sasaki Y, Takahashi H, Shimizu T. Five tips on clinical research mentorship for Japanese generalists. JHGM. 2022：4-3;170-1
　2021年

【原著（英文）】

  1. Nagasaki K, Nishizaki Y, Shinozaki T, Kobayashi H, Shimizu T, Okubo T, Yamamoto Y, Konishi R, Tokuda Y. Impact of the resident duty hours on in-training examination score: A nationwide study in Japan. Med Teach. 2021 Nov 24:1-8.
  2. Nagasaki K, Nishizaki Y, Nojima M, Shimuzu T, Konishi R, Okubo T, Yamamoto Y, Morishima R, Kobayashi H, Tokuda Y. Validation of the General Medicine In-training Examination Using the Professional and Linguistic Assessments Board Examination among Postgraduate Residents in Japan. Int J Gen Med. 2021;14:6487-6495.
  3. Kawamura R, Harada Y, Shimizu T. Diagnostic Effect of Consultation Referral from Gastroenterologists to Generalists in Patients with Undiagnosed Chronic Abdominal Pain: A Retrospective Study. Healthcare 2021;9(9):1150.
  4. Hirosawa T, Harada Y, Ikenoya K, Kakimoto S, Aizawa Y, Shimizu T. The Utility of Real-Time Remote Auscultation Using a Bluetooth-Connected Electronic Stethoscope: Open-Label Randomized Controlled Pilot Trial. JMIR Mhealth Uhealth 2021;9(7):e23109.
  5. Harada Y, Katsukura S, Kawamura R, Shimizu T. Effects of a Differential Diagnosis List of Artificial Intelligence on Differential Diagnoses by Physicians: An Exploratory Analysis of Data from a Randomized Controlled Study. Int J Environ Res Public Health. 2021 May 23;18(11):5562.
  6. Shimizu T. The 6C model for accurately capturing the patient’s medical history. Diagnosis (Berl). 2021 Apr 23. doi: 10.1515/dx-2020-0126. Epub ahead of print.
  7. Miyagami T, Harada T, Watari T, Shimizu T. Evaluating Cognitive Bias from Diagnostic Error Cases Using the Cognitive Bias Codex. J Hosp Gen Med, In Press 2021.
  8. Tago M, Watari T, Shikino K, Sasaki Y, Takahashi H, Shimizu T. A statement on the ten fascinating skills of the Japanese hospitalist. J Hosp Gen Med, In Press 2021.
  9. Nishizaki Y, Nozawa K, Shinozaki T, Shimizu T, Okubo T, Yamamoto Y, Konishi R, Tokuda Y. Difference in the general medicine in-training examination score between community-based hospitals and university hospitals: a cross-sectional study based on 15,188 Japanese resident physicians. BMC Med Educ. 2021 Apr 15;21(1):214.
  10. Harada Y, Katsukura S, Kawamura R, Shimizu T. Efficacy of Artificial-Intelligence-Driven Differential-Diagnosis List on the Diagnostic Accuracy of Physicians: An Open-Label Randomized Controlled Study. Int J Environ Res Public Health. 2021 Feb 21;18(4):2086.
  11. Miyagami T, Uehara Y, Harada T, Watari T, Shimizu T, Nakamura A, Ogura N, Kushiro S, Masuyama K, Kanai Y, Yang KS, Naito T. Delayed treatment of bacteremia during the COVID-19 pandemic. Diagnosis (Berl). 2021 Jan 19:dx-2020-0114.
  12. Hirosawa T, Harada Y, Nishinobu T, Honda Y, Morinaga K, Takase H, Shimizu T. The diagnostic value of Reversed Carnett’s sign for detecting intra-abdominal lesion in patients with acute abdominal pain. JHGM. 2021;3(1):11-20.

 

【症例報告（英文）】

  1. Nagase Y, Harada Y. Misdiagnosis of Rectus Abdominis Abscess Owing to Delayed Contrast-Enhanced Computed Tomography. Eur J Case Rep Intern Med. 2021 Dec 30;8(12):003097.
  2. Harada T, Shimizu T. Fitz-Hugh-Curtis syndrome without salpingitis: Should contrast-enhanced computed tomography be a routine diagnostic procedure? Clin Case Rep. 2021 Dec 13;9(12):e05211.
  3. Kawahigashi T, Shimizu T, Kawabe T, Kida Y, Watanabe K. Delayed Diagnosis of Pulmonary Embolism. Am J Med. 2022 Mar;135(3):e63-e64.
  4. Komaba W, Harada Y, Ishida Y, Tamashiro A, Tomita A. Into the Duct: An Unusual Source of Bacteremia. Am J Med. 2022 Mar;135(3):324-326.
  5. Sota T, Ohtani, Okuno S, Yamada H, Nanjo Y, Harada Y. Isolated muscular sarcoidosis that presented as acute myopathy. 2021;3-5:174-178.
  6. Kakimoto S, Harada Y, Shimizu T. Acute upper airway obstruction by a goitre due to Hashimoto’s thyroiditis. BMJ Case Rep. 2021 Sep 8;14(9):e245198.
  7. Kunitomo K, Shimizu T, Harada Y. A Case of Multiple Ring-Shaped Aphthae Without Pseudomembranous Colitis. Am J Med Sci. 2022 Mar;363(3):e25-e26.
  8. Miyagami T, Takada A, Shimizu T, Naito T. Delayed diagnosis of a piriformis abscess due to hyposkillia and communication error. BMJ Case Rep. 2021 Aug 11;14(8):e242088.
  9. Kawamura R, Suzuki Y, Harada Y, Shimizu T. Atypical presentation of colorectal carcinoma with sole multiple osteolytic bone metastases: a case report. J Med Case Rep. 2021 May 21;15(1):256.
  10. Kawahigashi T, Shimizu T, Kawabe T, Kida Y, Watanabe K. Missed Diagnosis of Subarachnoid Haemorrhage. Eur J Case Rep Intern Med. 2021 May 31;8(5):002616.
  11. Sakamoto T, Kaburaki M, Shimizu T. Salt-and-pepper skin appearance & Systemic sclerosis. QJM. 2021 May 6:hcab070.
  12. Yokose M, Shimizu T. A Case of Ramsay Hunt Syndrome That Began with Vestibular Symptoms: A Great Mimicker. Am J Med. 2021 Apr;134(4):e271-e272.
  13. Ito T, Harada Y, Shimizu T. Diagnostic and Management Errors in an Immunodeficient Patient with Pneumococcal Pneumonia with Bacteraemia due to Incorrect Assessment of the Patient’s Immune Status. Eur J Case Rep Intern Med. 2021 Apr 26;8(4):002557.
  14. Kano Y, Harada Y. Moist lesion in the third webspace of the fingers. BMJ. 2021;373:n729.
  15. Harada T, Sasaki Y, Tokunaga T, Yoshizawa A, Miura S, Ikeda K, Saito T, Hiroshige J. 18F-Fluorodeoxyglucose positron emission tomography computed tomography detection of single organ vasculitis of the breast: A case report. Medicine (Baltimore). 2021 Mar 26;100(12):e25259.
  16. Harada T, Harada Y, Shimizu T. Vertebral Artery Dissection after Exposure to Levofloxacin: A Report of Two Cases. Intern Med. 2021 Sep 1;60(17):2863-2865.
  17. Masuda M, Sakamoto T, Shimizu T. Wellens’ Syndrome. Am J Med Sci. 2021 Feb 20:S0002-9629(21)00066-5.
  18. Kawamura R, Harada Y, Shimizu T. Missed Diagnosis of Cholangiocarcinoma Presenting with Atypical Symptoms. Eur J Case Rep Intern Med. 2021 Jan 26;8(1):002207.

 

【その他（英文）】

  1. Tago M, Watari T, Shikino K, Sasaki Y, Takahashi H, Shimizu T. Five Tips for Becoming an Ideal General Hospitalist. Int J Gen Med. 2021 Dec 29;14:10417-10421.
  2. Tago M, Watari T, Shikino K, Yamashita S, Sasaki Y, Takahashi H, Shimizu T. Research trends of general hospitalists in Japan：a cross-sectional questionnaire-based personal survey. JHGM 2021;3-6:225-7.
  3. Harada T, Miyagami T, Watari T, Kawahigashi T, Harada Y, Shikino K, Shimizu T. Barriers to diagnostic error reduction in Japan. Diagnosis (Berl). 2021 Jun 30. doi: 10.1515/dx-2021-0055. Epub ahead of print. PMID: 34187115.
  4. Sakamoto T, Kaburaki M, Shimizu T. Nailfold capillaroscopy findings and systemic sclerosis. QJM. 2021 May 28:hcab156.
  5. Tago M, Watari T, Shikino K, Sasaki Y, Takahashi H, Shimizu T. A statement on the ten fascinating skills of the Japanese hospitalist. J Hosp Gen Med, In Press 2021.
  6. Shikino K, Watari T, Tago M, Sasaki Y, Takahashi H, Shimizu T. Five tips on writing case reports for Japanese generalists. J Gen Fam Med. 2021;22:111–112.
  7. Mizumoto J, Shimizu T. Clinical Problem Solving: Unforgettable in every way. J Gen Fam Med. In Press, 2021
  8. Mizumoto J, Shimizu T. Why‐not‐doing‐high‐tech‐test Syndrome. J Gen Fam Med. 2021;22:70–74.

 

【原著・総説・その他（和文）】

  1. 原田拓, 宮上泰樹, 綿貫聡, 和足孝之, 高橋宏瑞, 近藤猛, 志水太郎. 診断エラーワーキンググループの活動報告および診断エラーの歴史と文化に関する考察. 日本病院総合診療医学会雑誌 2021;17(4):448-452.
  2. 廣澤 孝信, 志水 太郎.【新型コロナウイルス感染症2019】総合診療からみたコロナ禍の外来診療と教育の要点. Dokkyo Journal of Medical Sciences(0385-5023)48巻3号 Page255-260(2021.10).
　2020年　　

【原著（英文）】

  1. Nishizaki Y, Shimizu T, Shinozaki T, Okubo T, Yamamoto Y, Konishi R, Tokuda Y. Impact of general medicine rotation training on the in-training examination scores of 11, 244 Japanese resident physicians: a Nationwide multi-center cross-sectional study. BMC Med Educ. 2020 Nov 13;20(1):426.
  2. Shimizu T. Horizontal and vertical tracing: a cognitive forcing strategy to improve diagnostic accuracy. Postgrad Med J. 2020 Oct;96(1140):581-583.
  3. Harada Y, Shimizu T. Impact of a Commercial Artificial Intelligence-Driven Patient Self-Assessment Solution on Waiting Times at General Internal Medicine Outpatient Departments: Retrospective Study. JMIR Med Inform. 2020 Aug 31;8(8):e21056.
  4. Hirosawa T, Harada Y, Morinaga K, Takase H, Nin M, Shimizu T. Eosinopenia as a diagnostic marker of bloodstream infection in a general internal medicine setting: a cohort study. BMC Infect Dis. 2020 Jan 30;20(1):85.
  5. Harada Y, Masuda M, Hirosawa T, Takase H, Morinaga K, Nin M, Shimizu T. Safety and efficacy of outpatient follow-up for referred patients with undiagnosed fever: A retrospective cohort study. Medicine (Baltimore). 2020 Jan;99(5):e18532.

 

【症例報告（英文）】

  1. Mizusawa K, Shimizu T. Three Cases of Food Poisoning Due to Paralepistopsis acromelalga Diagnosed from an Outbreak of Erythromelalgia. Intern Med. 2020 Dec 22.
  2. Ito T, Sawachika H, Harada Y, Shimizu T. The Dangers of Immediately Performing a Sensitive and Specific Investigation versus the Dangers of Delaying It: A Cautionary Case of Hodgkin’s Lymphoma. Eur J Case Rep Intern Med. 2020 Dec 1;7(12):002138.
  3. Akutagawa K, Kunitomo K, Shimizu T, Tsuji T. Organophosphate Poisoning: Vital Signs Are Not Vital In Diagnosis. QJM. 2020 Nov 27:hcaa319.
  4. Sakamoto T, Harada Y, Shimizu T. A Cat-and-Mouse Game? Multiple Abscesses Due to Staphylococcus aureus Bacteremia. Am J Med. 2021 Jun;134(6):e392-e393.
  5. Kano Y, Harada Y. Popliteal Ecchymosis in Ruptured Baker’s Cyst. Am J Med. 2021 Apr;134(4):e277.
  6. Kuwabara R, Harada Y. Is a Gallbladder Coming Back? A Seroma in the Gallbladder Fossa. Am J Med. 2021 May;134(5):e327-e328.
  7. Harada T, Watari T, Miyagami T, Watanuki S, Shimzu T, Hiroshige J. COVID Blindness: Delayed Diagnosis of Aseptic Meningitis in the COVID-19 Era. Eur J Case Rep Intern Med. 2020 Oct 23;7(11):001940.
  8. Harada Y, Shimizu T. Delayed Diagnosis of Pulmonary Thromboembolism Due to Overfocus on COVID-19. Eur J Case Rep Intern Med. 2020 Oct 21;7(11):002002.
  9. Kikuchi K, Yasui-Furukori N, Yokoyama S, Hasegawa C, Kokubun A, Katsukura S, Shimizu T, Shimoda K. Clozapine-associated severe eosinophilia following lithium rebound neutropenia: A case report. Neuropsychopharmacol Rep. 2020 Sep 19.
  10. Shimizu T. Elderly woman with swollen leg. J Am Coll Emerg Physicians Open. 2020 Sep 7;1(5):1149-1150.
  11. Miyagami T, Harada T, Terukina H, Komori A, Watari T, Shimizu T, Naito T. Diagnostic Difficulties in Treating a Typical Case of a Patient Being a Doctor. Am J Med. 2020 Jul 10:S0002-9343(20)30551-9.
  12. Harada Y, Kakimoto S, Shimizu T. Pazopanib-associated interstitial lung disease in a patient with renal cell carcinoma. BMJ Case Rep. 2020 Jul 8;13(7):e235177.
  13. Shimizu T. Synchronous Bilateral Spontaneous Pneumothorax. Am J Med Sci. 2020 Jun 7:S0002-9629(20)30248-2.
  14. Sato Y, Shinozaki M, Sasaki H, Shiinoki M, Shimizu T, Yasui-Furukori N, Shimoda K. Gluten-Related Disorder and Lactose Intolerance Concomitant With Avoidant/Restrictive Food Intake Disorder. Prim Care Companion CNS Disord. 2020 Jul 2;22(4):19l02517.
  15. Wada T, Harada T, Ikeda K, Hiroshige J. Spontaneous spinal epidural haematoma due to polypharmacy including multiple antiplatelet agents. Postgrad Med J. 2020 Jun 23:postgradmedj-2020-137755.
  16. Hirosawa T, Sakamoto T, Shimizu T. Gastric Anisakiasis. Am J Med Sci. 2020 Sep;360(3):318-319.
  17. Fukuda M, Harada T, Shimizu T, Hiroshige J. Forchheimer Spots in Rubella. Intern Med. 2020 Jul 1;59(13):1673.
  18. Hirosawa T, Shimizu T. Brachiocephalic Vein Thrombosis. Am J Med Sci. 2020 May;359(5):306-307.
  19. Yokose M, Harada Y, Shimizu T. Behind the Leg: Cryptococcal Meningitis, Not Cellulitis. Am J Med. 2020 Mar;133(3):e81-e82.
  20. Uehara K, Harada Y. Misdiagnosis of Liver Abscess Resulting From Misunderstood Culture Results. Am J Med. 2020 Feb;133(2):e44-e45.
  21. Hirosawa T, Katsukura S, Shimizu T. SAPHO Syndrome. Am J Med Sci. 2020 Jan;359(1):e5-e6.

 

【その他（英文）】

  1. Harada T, Shimizu T, Kaji Y, Suyama Y, Matsumoto T, Kosaka C, Shimizu H, Nei T, Watanuki S. A Perspective from a Case Conference on Comparing the Diagnostic Process: Human Diagnostic Thinking vs. Artificial Intelligence (AI) Decision Support Tools. Int J Environ Res Public Health. 2020 Aug 22;17(17):6110.
  2. Yokose M, Harada Y, Shimizu T. The Reply. Am J Med. 2020 Jun;133(6):e328.
  3. Uehara K, Harada Y. The Reply. Am J Med. 2020 May;133(5):e211.
  4. Terui T, Mizumoto J, Harada Y, Ohya A, Takeda Y. A report of the Social Vital Signs Workshop at WONCA Asia Pacific Regional Conference 2019. J Gen Fam Med. 2020 Feb 18;21(3):92-93.

 

【原著・総説（和文）】

  1. 志水太郎. AIの臨床診断学への応用. アレルギー. 2020 Sep;69(8): 658-661.
  2. 志水太郎. ─脳研究の最前線─意識障害をきたす内科疾患，その考え方. Dokkyo Journal of Medical Sciences 2020;47(3）：253-257.
　2019年　　

【原著・総説】

  1. Shimizu T. Reflection Of Reflections: Building Diagnostic Expertise. Int J Gen Med. 2019 Oct 7;12:363-365.
  2. Norii T, Homma Y, Shimizu H, Takase H, Kim SH, Nagata S, Shimosato A, Crandall C; Japanese Procedural Sedation and Analgesia Registry investigators. Procedural sedation and analgesia in the emergency department in Japan: interim analysis of multicenter prospective observational study. J Anesth. 2019 Apr;33(2):238-249.

 

【症例報告】

  1. Yokoyama N, Shiraki R, Watanabe T, Shiinoki M, Nin M, Shimizu T, Yasui-Furukori N, Shimoda K. Difficult differentiation of a somatic symptom disorder from anterior cutaneous nerve entrapment syndrome (ACNES): a case report. BMC Psychiatry. 2019 Dec 12;19(1):394.
  2. Takase H, Shimizu T. Erythema nodosum-like lesion on heel in a patient assumed Behçet’s disease. BMJ Case Rep. 2019 Nov 19;12(11):e232056.
  3. Sakamoto T, Takase H, Shimizu T. Secretion from umbilicus. BMJ Case Rep. 2019 Aug 15;12(8):e231139.
  4. Mitsutake A, Harada Y, Tomita A, Ueshima K. Intramural haematoma of the oesophagus. BMJ Case Rep. 2019 Jul 10;12(7):e230433.
  5. Shimizu T, Harada Y. Preauricular Vertical Creases. Intern Med. 2019 Oct 15;58(20):3067.
  6. Tanaka M, Harada T. Koplik spots in measles. Postgrad Med J. 2019 Aug;95(1126):454.
  7. Notomi K, Harada T. Achenbach syndrome. CMAJ. 2019 May 27;191(21):E584.
  8. Hirosawa T, Shiinoki M, Shimizu T. Cerebral Venous Thrombosis. Am J Med Sci. 2019 Jul;358(1):e3.
  9. Harada Y, Hayashi M. Severe leptospirosis in a patient with positive serological test for spotted fever rickettsiosis. BMJ Case Rep. 2019 Jan 10;12(1):bcr-2018-226514.

 

【その他】

  1. Mizumoto J, Shimizu T. All that glitters is not gold. J Gen Fam Med. 2019 Jul 4;20(5):180-184.
  2. Mizumoto J, Terui T, Komatsu M, Ohya A, Suzuki S, Horo S, Sugihara D, Otaka Y, Ashino A, Imura H, Harada Y, Sato K. Social vital signs for improving awareness about social determinants of health. J Gen Fam Med. 2019 May 2;20(4):164-165.
  3. Shimizu T. Author Reply: Lumbar Kyphosis. Intern Med. 2019 Jul 1;58(13):1977.

 

【原著・総説（和文）】

  1. 高瀬啓至, 深野賢太朗, 茂木章一郎, 本間洋輔, 乗井達守. 市中の救急外来における処置時の鎮静・鎮痛の実施状況と安全性の検討. 麻酔. 2019 Oct;68(10):1064-1072.

 

【症例報告（和文）】

  1. 岩上明憲, 藤澤大輔, 梅川浩平, 菅剛史, 朝戸裕貴, 志水太郎. 形成外科医が出会う可能性がある腹痛　外科的治療を行ったanterior cutaneous nerve entrapment syndrome(ACNES)の3例. 形成外科. 2019 Nov;62(11):1293-1299.

 

【その他（和文）】

  1. 高瀬啓至, 志水太郎. 診断エラー改善のための臨床推論教育. ジェネラリスト教育コンソーシアム. 2019 Dec;13:98-108.
　2018年　　

【原著・総説】

  1. Amano M, Shimizu T. Mondor’s Disease: A Review of the Literature. Intern Med. 2018 Sep 15;57(18):2607-2612.
  2. Nishizaki Y, Shinozaki T, Kinoshita K, Shimizu T, Tokuda Y. Awareness of Diagnostic Error among Japanese Residents: a Nationwide Study. J Gen Intern Med. 2018 Apr;33(4):445-448.
  3. Shimizu T, Nemoto T, Tokuda Y. Effectiveness of a clinical knowledge support system for reducing diagnostic errors in outpatient care in Japan: A retrospective study. Int J Med Inform. 2018 Jan;109:1-4.

 

【症例報告】

  1. Harada Y, Komori I, Morinaga K, Shimizu T. Microangiopathic haemolytic anaemia with thrombocytopenia induced by vitamin B12 deficiency long term after gastrectomy. BMJ Case Rep. 2018 Sep 19;2018:bcr2018225915.
  2. Arai T, Kogi K, Honda Y, Suzuki T, Kawai K, Okamoto M, Fujioka T, Murata N. Lorazepam as a Cause of Drug-Induced Liver Injury. Case Rep Gastroenterol. 2018 Aug 31;12(2):546-550.
  3. Hirosawa T, Shimizu T. Osmotic demyelination syndrome due to hyperosmolar hyperglycemia. Cleve Clin J Med. 2018 Jul;85(7):511-513.
  4. Jinno A, Hirosawa T. Aortic intramural haematoma associated with pulmonary artery periadventitial haematoma. BMJ Case Rep. 2018 May 18;2018:bcr2018224853.
  5. Shimizu T. Severe Hyperkyphosis. Intern Med. 2018 Aug 1;57(15):2281.
  6. Jinno A, Hirosawa T, Shimizu T. Hepatic portal venous gas after diving. BMJ Case Rep. 2018 Jan 12;2018:bcr2017223844.
  7. Kamijo C, Harada Y. Delayed Diagnosis of Cast Nephropathy. Am J Med. 2018 Jan;131(1):e23.

 

【その他】

  1. Watanuki S, Sada R, Ishikane M, Shimizu T, Kutsuna S. The Tokyo GIM Conference: Clinical reasoning conference from real cases. J Gen Fam Med. 2018 Sep 24;19(6):228.
　2017年　　

【原著・総説】

  1. Nishizaki Y, Mizuno A, Shinozaki T, Okubo T, Tsugawa Y, Shimizu T, Konishi R, Yamamoto Y, Yanagisawa N, Shiojiri T, Tokuda Y. Educational environment and the improvement in the General Medicine In-training Examination score. J Gen Fam Med. 2017 Apr 13;18(5):312-314.

 

【症例報告】

  1. Shibaike Y, Hirosawa T, Shimizu T. Shell in the rectum. BMJ Case Rep. 2017 Jul 5;2017:bcr2017221125.
  2. Morinaga K, Yamanaka K. Concomitant crystal-induced and septic arthritis. IDCases. 2017 Jun 27;9:97.
  3. Harada Y. Transient T-wave changes in Guillain-Barré syndrome. J Gen Fam Med. 2017 Jun 21;18(6):460-461.
  4. Morinaga K, Shimizu T. Diagnosing Bilateral Tarsal Tunnel Syndrome. Am J Med. 2017 Oct;130(10):e437-e438.
  5. Nemoto T, Tokuda Y, Hirose M, Naitoh Y, Yamasaki Y, Shimizu T, Nishisako H, Kunishima H, Matsuda T. Thoracic Aortic Graft Infection due to Candida Albicans with Multiple Embolism in the Left-side Vessels of the Body. Intern Med. 2017;56(9):1107-1111.
  6. Harada T, Hirosawa T, Morinaga K, Shimizu T. Metoclopramide-induced Serotonin Syndrome. Intern Med. 2017;56(6):737-739.
  7. Harada T, Suyama Y, Hiratsuka Y, Shimizu T. An Arterial Perihepatic Enhancement Caused by Spontaneous Bladder Rupture. Urology. 2017 Feb;100:e7-e8.

 

【その他（和文）】

  1. 志水太郎. 運営・管理の道具箱(第1回)　強いチームの作り方. プライマリ・ケア. 2017 Jun;2(2):43-45.
　2016年　　

【原著・総説】

  1. Mizuno A, Tsugawa Y, Shimizu T, Nishizaki Y, Okubo T, Tanoue Y, Konishi R, Shiojiri T, Tokuda Y. The Impact of the Hospital Volume on the Performance of Residents on the General Medicine In-Training Examination: A Multicenter Study in Japan. Intern Med. 2016;55(12):1553-8.doi: 2169/internalmedicine.55.6293. Epub 2016 Jun 15.

 

【症例報告】

  1. Hirosawa T, Shimizu T, Isegawa T, Tanabe M. Left pleural effusion caused by pancreaticopleural fistula with a pancreatic pseudocyst. BMJ Case Rep. 2016 Aug 24;2016:bcr2016217175.
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獨協医科大学病院 総合診療科で実施の研究一覧

研究課題名
感染性心内膜炎チーム設立に伴う感染性心内膜炎診療の変化：後ろ向き観察研究
大学病院総合診療科から他科へのコンサルテーションの内容と結果に関する横断研究
大学病院総合診療科に院内他科から紹介される患者の診断に関する横断研究
大学病院入院中に院内他科から総合診療科へ行われるコンサルテーションの内容と結果に関する横断研究
大学病院総合診療科における診断エラー検証のための後ろ向き観察研究
熱源不明の症例に対する感染性心内膜炎の予測モデルの開発：多施設後ろ向き観察研究
獨協医科大学病院における黄色ブドウ球菌菌血症に対する治療介入の質の評価と介入の要否及び方法の検討
獨協医科大学病院総合診療科の外来と入院における漢方処方の比較に関する観察研究
総合診療科の連携診療における眼病変から全身性疾患を疑う患者の診断および治療に関する観察研究
血液培養もしくは尿培養から起因菌を検出した尿路感染症の入院症例における経口抗生剤への変更に関連する因子についての後方視的研究

研究情報の公開について（オプトアウト）

通常、臨床研究を実施する際には、文書もしくは口頭で説明・同意を得て実施をしますが、臨床研究のうち、患者さまへの侵襲及び介入を伴わず、診療情報等の情報のみを用いた研究等については、国が定めた指針に基づき「研究対象となる患者さまのお一人ずつから文書または口頭による同意を得る必要はありません」とされています。しかし、その際は研究の目的を含めて研究の実施についての情報を公開し、さらに拒否の機会を保障することが必要とされます。このような手法を「オプトアウト」と言います。

オプトアウトを用いた臨床研究は下記の通りです。尚、研究への協力を希望されない場合は、下記文書内に記載されている各研究の担当者までお知らせください。

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