ARTICLES&RESEARCH

ARTICLES&
RESEARCH

論文／研究

CONTENTS SELECTOR

原著(英文)

  1. Tago M, Shikino K, Yoshinaga R, Takahashi H, Harada Y, Matsuda N, Suzuki T, Watari T, Sasaki Y, Shimizu T. Redefining the Role of General Medicine Physicians in the Artificial Intelligence Era: Implications for Clinical Practice and Education. J Hosp Gen Med. 2025;8:503-508.
  2. Shikino K, Tago M, Watari T, Sasaki Y, Takahashi H, Hirata R, Shimizu T. Key Clinical strategies on outpatient care for Japanese general medicine physicians. J Hosp Gen Med. 2025;7(2):70-73.
  3. Kunitomo K, Tsuji T, Kouzaki Y, Yoshimura F, Kubosaki J, Shimizu T. Factors Affecting Diagnostic Difficulties in Aseptic Meningitis: A retrospective observational study. Diagnosis. 2025. In Press.
  4. Fujikawa H, Tamune H, Nishizaki Y, Shikino K, Shimizu T, Yamamoto Y, Tokuda Y. Undergraduate general medicine education in Japan: a nationwide cross-sectional survey of medical trainees’ perspectives. J Gen Fam Med. 2025;26:148-156.
  5. Harada T, Watari T, Watanuki S, Kuhiro S, Miyagami T, Syusa S, Suzuki S, Hiyoshi T, Hasegawa S, Nabeshima S, Aihara H, Yamashita S, Tago M, Yoshimura F, Kunitomo K, Tsuji T, Hiroe M, Tsuchida T, Shimizu T. Preventable diagnostic errors of lower gastrointestinal perforation: a secondary analysis of a large-scale multicentre retrospective study. Int J Emerg Med. 2025 In Press.
  6. Miyagami T, Nogi M, Saita M, Takahashi H, Hirata R, Tokushima Y, Kawamura R, Tago M, Shimizu T, Naito T, Tazuma S. Executive meeting report between the Japanese Society of Hospital General Medicine and the Society of Hospital Medicine. J Hosp Gen Med. 2025;7(1):25-28.
  7. Izumoto J, Shimizu T. Homemade and Handmade. J Gen Fam Med. 2025 Oct 23;26(6):534-538. doi: 10.1002/jgf2.70077. PMID: 41195031; PMCID: PMC12585804.
  8. Amano M, Watari T, Shimizu T. The clinical roles of generalists in Japan: A descriptive model of problem setting and problem-solving. J Gen Fam Med. 2025 Jun 30;26(6):501-503.
  9. Shimizu T, Watanuki S, Harada Y, Kawamura R, Amano M, Isoda S, Kunitomo K, Komatsu M, Miyagami T, Ishizuka K, Kosaka S, Kurihara M. Pioneering diagnosis in Asia: advancing clinical reasoning expertise through the lens of 3M. Diagnosis (Berl). 2025 Feb 10;12(2):145-148.
  10. Miyagami T, Ishizuka K, Furusaka-Kushiro S, Kondo K, Kunitomo K, Akutagawa K, Watari T, Harada T, Ito H, Ando T, Hiyoshi T, Harada Y, Yamashita S, Nishizaki Y, Shimizu T, Raffel KE, Naito T. A mixed methods study comparing video based and paper based diagnostic error education for medical students. Sci Rep. 2025 Dec 11. doi: 10.1038/s41598-025-32396. Epub ahead of print. PMID: 41372568.
  11. Yokose M, Hirosawa T, Sakamoto T, Kawamura R, Suzuki Y, Harada Y, Shimizu T. The Validity of Generative Artificial Intelligence in Evaluating Medical Students in Objective Structured Clinical Examination: Experimental Study. JMIR Form Res. 2025 Dec 4;9:e79465.
  12. Shimizu I, Shikino K, Harada Y, Kurihara M, Tanaka K, Masuda Y, Watanuki S, Ohishi Y, Nakazato T, Ishizuka K, Komatsu M, Miyagami T, Nishizawa T, Nishimura R, Oshita T, Suzuki T, Shimizu T. Differences in contributing factors to diagnostic errors between physicians and allied health professionals: a nationwide analysis in Japan. BMJ Open Qual. 2025 Nov 24;14(4):e003419.
  13. Hirosawa T, Harada Y, Shimizu T. Transforming world and word: a longitudinal analysis of verb usage within English abstracts from medical articles. AI & Soc. 2025. https://doi.org/10.1007/s00146-025-02750-8
  14. Katayama K, Takata T, Nishizaki Y, Nagasaki K, Shimizu T, Yamamoto Y, Watari T, Tokuda Y, Chopra V, Ohira Y. Time-at-bedside and competency acquisition: a secondary analysis of GM-ITE domain scores in Japanese resident physicians. BMC Med Educ. 2025 Nov 3;25(1):1537.
  15. Fujikawa H, Tamune H, Nishizaki Y, Shikino K, Shimizu T, Yamamoto Y, Sekine M, Nagasaki K, Kobayashi H, Tokuda Y. Supervising physicians’ perceptions on physician work-hour regulations in Japan: a nationwide cross-sectional study. BMC Med Educ. 2025 Oct 24;25(1):1489.
  16. Shimizu T, Hautz WE, van Sassen C, Zwaan L. The global progress for improving diagnosis: what we’ve learned, what comes next. Diagnosis (Berl). 2025 Sep 18;12(4):529-537.
  17. Sakamoto T, Hirosawa T, Harada Y, Shibasaki I, Sairenchi T, Nishikawa R, Sakikawa H, Shimizu T. Impact of an Infective Endocarditis Team on Management and Outcomes: A Retrospective Cohort Study. Int J Gen Med. 2025;18:5743-5754.
  18. Kunitomo K, Harada Y, Watari T, Harada T, Shimizu T. Diagnostic errors in older patients: a secondary analysis of case reports. Diagnosis (Berl). 2025 Sep 16. doi: 10.1515/dx-2025-0073. Epub ahead of print. PMID: 40966580.
  19. Tago M, Hirata R, Shikino K, Watari T, Takahashi H, Nishii T, Sasaki Y, Shimizu T. A Classification Method for General Medicine Physicians to Advance Field Research in Japan. Int J Gen Med. 2025 Sep 1;18:5033-5038.
  20. Isoda S, Shimizu T, Shimoto T, Shimada F, Misawa M, Suzuki T. A Reflective Verbalization Strategy to Trigger Alternative Diagnostic Hypotheses. J Eval Clin Pract. 2025 Sep;31(6):e70267.
  21. Kawahigashi T, Taisuke J, Shimizu T, Isogai N, Ogino H, Takagi T, Watanabe K, Yasunaga H, Kawachi J. Delay in Surgery for Ruptured Aortic Aneurysm in Hemodynamically Stable Patients: A Multicenter Retrospective Analysis. Cureus. 2025 Aug 3;17(8):e89294.
  22. Shikino K, Nishizaki Y, Kataoka K, Nagasaki K, Kobayashi H, Shimizu T, Tokuda Y. Optimal Working Hours in the 2024 Physician Work Reform: Insights from a Residency Program Director. Adv Med Educ Pract. 2025 Aug 20;16:1461-1468.
  23. Kamiya S, Nishizawa T, Ozawa H, Harada Y, Watari T, Shimizu T, Sakurai M, Suzuki Y, Deshpande GA, Arioka H. Association between referral letters and diagnostic errors: a single-center, cross-sectional study in general internal medicine in Japan. Diagnosis (Berl). 2025 Aug 22;13(1):46-54. doi: 10.1515/dx-2024-0197. PMID: 40838630.
  24. Tago M, Sasaki Y, Katsuki N, Hirata R, Aihara H, Komatsu F, Une K, Miyagami T, Suzuki Y, Kawamura R, Takeoka H, Yasuoka Y, Shimizu T, Nabeshima S, Naito T, Tazuma S. Features of Undiagnosed Abdominal Pain and Diagnostic Status of Acute Hepatic Porphyria in Japan: A Retrospective Study. Int J Med Sci. 2025;22(12):3014-3021.
  25. Hirosawa T, Yokose M, Sakamoto T, Harada Y, Tokumasu K, Mizuta K, Shimizu T. Utility of Generative Artificial Intelligence for Japanese Medical Interview Training: A Randomized Crossover Pilot Study. JMIR Med Educ. 2025;11:e77932.
  26. Shikino K, Nishizaki Y, Fukui S, Kataoka K, Yokokawa D, Shimizu T, Yamamoto Y, Nagasaki K, Kobayashi H, Tokuda Y. Resident Physician Recognition of Tachypnea in Clinical Simulation Videos in Japan: Cross-Sectional Study. JMIR Med Educ. 2025 Jul 31;11:e72640.
  27. Shimizu T. Diagnostic uncertainty in physicians’ reasoning: a structured approach using BANI and GRACE2. Diagnosis (Berl). 2025 Jul 23;13(1):20-27. doi: 10.1515/dx-2025-0059. PMID: 40693811.
  28. Shimizu T. Learning from what goes right: a safety-II framework for improving diagnosis at the point of care. Diagnosis (Berl). 2025 Jul 17. doi: 10.1515/dx-2025-0086. Epub ahead of print. PMID: 40667991.
  29. Tago M, Sasaki Y, Katsuki N, Hirata R, Aihara H, Komatsu F, Une K, Miyagami T, Suzuki Y, Kawamura R, Takeoka H, Yasuoka Y, Shimizu T, Nabeshima S, Naito T, Tazuma S. Features of Undiagnosed Abdominal Pain and Diagnostic Status of Acute Hepatic Porphyria in Japan: A Retrospective Study. Int J Med Sci. 2025 Jun 20;22(12):3014-3021.
  30. Fujikawa H, Tamune H, Nishizaki Y, Shikino K, Shimizu T, Yamamoto Y, Kobayashi H, Tokuda Y. Hospital Type and Medical Residents’ Patient Care Ownership: A Nationwide Cross-Sectional Study in Japan. Clin Teach. 2025 Aug;22(4):e70109.
  31. Nagasaki K, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Kobayashi H, Tokuda Y. Educational environment changes toward resident duty hour restrictions in Japan. Sci Rep. 2025 May 15;15(1):16925.
  32. Tago M, Hirata R, Kawamura R, Kawaguchi M, Tsuruta K, Tokushima Y, Shikino K, Watari T, Takahashi H, Sasaki Y, Shimizu T. Current Status and Recommendations for Improving the Specialty Program of the Hospital General Medicine Society: Insights from Discussions at the 30th Japan Society of Hospital General Medicine Annual Meeting. J Hosp Gen Med. 2025 May;7(5):222-5.
  33. Miyagami T, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Nojima M, Deshpande GA, Naito T, Tokuda Y. Evaluating the Use of a Note-Taking App by Japanese Resident Physicians: Nationwide Cross-Sectional Study. JMIR Form Res. 2025 May 9;9:e55087.
  34. Isoda S, Shimizu T, Hashimoto T, Hattori M, Suzuki T. Creativity and diagnostic reasoning. Diagnosis (Berl). 2025 May 6. doi: 10.1515/dx-2025-0015. Epub ahead of print. PMID: 40321020.
  35. Shimizu T. Physicians’ prism: Illuminating history with structured expertise. Diagnosis (Berl). 2025 Apr 1;12(3):333-340.
  36. Nishizawa T, Ishizuka K, Miyagami T, Kondo K, Takai S, Fukushima K, Kato D, Nishizaki Y, Shimizu T. Five Strategies for Efficient and Effective Training of Japanese Resident Physicians Under the Japanese Work Style Reform. Adv Med Educ Pract. 2025 Apr 5;16:577-581.
  37. Fujikawa H, Tamune H, Nishizaki Y, Nagasaki K, Kobayashi H, Nojima M, Sekine M, Shimizu T, Yamamoto Y, Shikino K, Tokuda Y. Association between residents’ work hours and patient care ownership: a nationwide cross-sectional study in Japan. BMC Med Educ. 2025 Mar 15;25(1):385.
  38. Fujikawa H, Tamune H, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Sekine M, Kobayashi H, Tokuda Y. Association of clinical knowledge with patient care ownership among resident physicians: a nationwide cross-sectional study in Japan. BMC Med Educ. 2025 Jan 16;25(1):77.
  39. Miyagami T, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Nojima M, Deshpande G, Naito T, Tokuda Y. Optimal outpatient training for resident physicians’ general medicine in-training examination score: a cross-sectional study. BMC Med Educ. 2025 Jan 11;25(1):49.
  40. Watanabe Y, Miyagami T, Shimizu T, Nishizaki Y, Ukishima S, Santo K, Furusaka Kushiro S, Aoki N, Suzuki M, Kanazawa A, Naito T. Diagnostic errors in patients admitted directly from new outpatient visits. Diagnosis (Berl). 2025 Jan 1;12(2):223-231.

 

【総説（英文）】

  1. 1Harada T, Miyagami T, Harada Y, Shimizu T. Diagnostic errors in acute cholecystitis: a scoping review. Diagnosis (Berl). 2025 Oct 2. doi: 10.1515/dx-2025-0061. Epub ahead of print. PMID: 41091049.
  2. Harada Y, Kawamura R, Yokose M, Singh H, Shimizu T. Atypical Presentations at Risk for Diagnostic Errors in Internal Medicine: A Scoping Review. J Gen Intern Med. 2025 Oct 14. doi: 10.1007/s11606-025-09901-z. Epub ahead of print. PMID: 41085962.
  3. Hirosawa T, Shimizu T. A Narrative Review of Artificial Intelligence in Medical Diagnostics. Computers, Materials & Continua. 2025, 83 (3), 3919-3944.
  4. Kano Y, Harada Y, Nishizawa T, Shimizu T. A scoping review of fever of unknown origin with normal serum C-reactive protein. Diagnosis (Berl). 2025 Apr 11;12(3):304-312.
  5. Kunitomo K, Harada Y, Suzuki T, Ishizuka K, Nishizawa T, Kawamura R, Miyagami T, Harada T, Watanuki S, Shimizu T, Kurihara M, Koizumi S. Identification and analysis of the evidence gaps in the field of diagnostic errors research in Japan: a scoping review. Diagnosis. 2026. In Press.
  6. Hirosawa T, Shimizu T. “Studies from Dokkyo Medical University in the Area of Artificial Intelligence Described (A Narrative Review of Artificial Intelligence In Medical Diagnostics).” Obesity, Fitness & Wellness Week, 28 June 2025, p. 3235. Gale OneFile: Health and Medicine, link.gale.com/apps/doc/A844920778/HRCAu=anon~3d7884e2&sid=sitemap&xid=54ad69a5. Accessed 1 Oct. 2025.
  7. Tateishi K, Mano T, Aoyama R, Hao K, Taniguchi T, Kojima S, Arai M, Minami Y, Yokose M, Kondo T, Tanaka A, Matsuo K, Yamaguchi J, Yamamoto T, Nakayama N, Hanada H, Hashiba K, Nakashima T, Matoba T, Tahara Y, Nonogi H, Noguchi T, Tsujimoto Y, Kikuchi M; Japan Resuscitation Council (JRC) Acute Coronary Syndrome (ACS) Task Force and the Guideline Editorial Committee on behalf of the Japanese Circulation Society (JCS) Emergency and Critical Care Committee. Clinical Benefits of Coronary Computed Tomography Angiography for Evaluating Low-Risk Patients With Non-ST-Elevation Acute Coronary Syndrome in the Emergency Department　- Systematic Review and Meta-Analysis. Circ Rep. 2025 Jul 27;7(9):705-714.
  8. Hao K, Taniguchi T, Kojima S, Arai M, Aoyama R, Tateishi K, Minami Y, Yokose M, Tanaka A, Matsuo K, Yamaguchi J, Mano T, Yamamoto T, Nakayama N, Hanada H, Hashiba K, Nakashima T, Kondo T, Noguchi T, Tsujimoto Y, Matoba T, Funazaki T, Tahara Y, Nonogi H, Kikuchi M; Japan Resuscitation Council (JRC) Emergency Cardiovascular Care (ECC) Acute Coronary Syndrome (ACS) Task Force and the Guideline Editorial Committee on behalf of the Japanese Circulation Society (JCS) Emergency and Critical Care Committee. Early Invasive Strategy in Non-ST-Elevation Acute Coronary Syndrome With Congestive Heart Failure　- A Systematic Review and Meta-Analysis. Circ Rep. 2025 Jul 27;7(9):697-704.
  9. Kitai T, Kawaji T, Hosaka Y, Sangawa M, Shiomi H, Hiraoka E, Sakamoto K, Iijima K, Yokose M, Noguchi T, Takahashi H, Matoba T, Kikuchi M, Tahara Y, Nonogi H, Funazaki T; Japan Resuscitation Council (JRC) Emergency Cardiovascular Care (ECC) Arrhythmia Task Force and the Guideline Editorial Committee on behalf of the Japanese Circulation Society (JCS) Emergency and Critical Care Committee. Should Sedative Administration Be Recommended as an Antiarrhythmic Therapy to Suppress Ventricular Fibrillation and Ventricular Tachycardia in Patients With Electrical Storm?　- A Scoping Review. Circ Rep. 2025 Oct 7;7(12):1149-1153.
  10. Arai M, Minami Y, Yamaguchi J, Tanaka A, Matsuo K, Mano T, Kojima S, Hao K, Taniguchi T, Tateishi K, Aoyama R, Yokose M, Noguchi T, Tsujimoto Y, Matoba T, Funazaki T, Tahara Y, Nonogi H, Kikuchi M; Japan Resuscitation Council (JRC) Emergency Cardiovascular Care (ECC) Acute Coronary Syndrome (ACS) Task Force and the Guideline Editorial Committee on behalf of the Japanese Circulation Society (JCS) Emergency and Critical Care Committee. Diagnostic Accuracy of the Initial Point-of-Care Troponin Tests for Patients With Chest Pain Who Were Suspected of Acute Myocardial Infarction　- A Systematic Review and Meta-Analysis. Circ Rep. 2025 Sep 20;7(11):997-1004.
  11. Aoyama R, Tateishi K, Mano T, Hao K, Taniguchi T, Kojima S, Arai M, Minami Y, Yokose M, Tanaka A, Matsuo K, Yamaguchi J, Noguchi T, Tsujimoto Y, Funazaki T, Matoba T, Tahara Y, Nonogi H, Kikuchi M; Japan Resuscitation Council (JRC) Emergency Cardiovascular Care (ECC) Acute Coronary Syndrome (ACS) Task Force and the Guideline Editorial Committee on behalf of the Japanese Circulation Society (JCS) Emergency and Critical Care Committee. Impact of Risk Stratification on Clinical Outcomes in Patients With Acute Coronary Syndrome　- A Systematic Review. Circ Rep. 2025 Sep 18;7(11):1005-1013.
  12. Sakamoto K, Iijima K, Kawaji T, Kitai T, Hosaka Y, Sangawa M, Shiomi H, Yokose M, Hiraoka E, Takahashi H, Matoba T, Kikuchi M, Tahara Y, Nonogi H, Noguchi T, Tsujimoto Y, Funazaki T; Japan Resuscitation Council (JRC) Emergency Cardiovascular Care (ECC) Arrhythmia Task Force and the Guideline Editorial Committee on behalf of the Japanese Circulation Society (JCS) Emergency and Critical Care Committee. Preventive Effect of Nifekalant on Recurrent Ventricular Fibrillation and Electrical Storm　- A Systematic Review and Meta-Analysis. Circ Rep. 2025 Sep 5;7(11):1029-1036.
  13. Sangawa M, Shiomi H, Hiraoka E, Sakamoto K, Iijima K, Kawaji T, Kitai T, Hosaka Y, Yokose M, Noguchi T, Takahashi H, Matoba T, Kikuchi M, Tahara Y, Nonogi H, Funazaki T; Japan Resuscitation Council (JRC) Emergency Cardiovascular Care (ECC) Arrhythmia Task Force and the Guideline Editorial Committee on behalf of the Japanese Circulation Society (JCS) Emergency and Critical Care Committee. Safety and Efficacy of Intravenous Magnesium for Torsade de Pointes　- A Scoping Review. Circ Rep. 2025 Oct 11;7(11):1037-1043.
  14. Yokose M, Sangawa M, Shiomi H, Sakamoto K, Iijima K, Kawaji T, Kitai T, Hosaka Y, Hiraoka E, Noguchi T, Takahashi H, Matoba T, Kikuchi M, Tahara Y, Nonogi H, Funazaki T; Japan Resuscitation Council (JRC) Emergency Cardiovascular Care (ECC) Arrhythmia Task Force and the Guideline Editorial Committee on behalf of the Japanese Circulation Society (JCS) Emergency and Critical Care Committee. Initial Dose of Intravenous Atropine for Patients With Symptomatic Bradycardia　- A Scoping Review. Circ Rep. 2025 Sep 27;7(11):1044-1050.

 

【症例報告（英文）】

  1. Miyazaki M, Kawamura R, Shimizu T. Teaching NeuroImage: Isolated Hypoglossal Nerve Palsy From Tuberculous Abscess. Neurology. 2025 Dec 23;105(12):e214419.
  2. Kawamura R, Enokihara T, Tsukinaga Y, Shimizu T. Recurrent anorexia because of gastrointestinal beriberi in a home care patient. J Gen Fam Med. 2025 Sep 16;26(6):637-641.
  3. Nozaki S, Yabuki T, Shimizu T. Secondary lung abscess caused by an esophagorespiratory fistula in a patient with a past history of heavy alcohol consumption. J Gen Fam Med. 2025 Aug 23;26(6):634-636.
  4. Sato Y, Sakamoto T, Harada Y, Shimizu T. Involuntary Movements of the Tongue in Transient Myoclonic State With Asterixis. Neurology. 2025 Oct 21;105(8):e214213.
  5. Kawamura R, Suzuki T, Matsuda H, Ishida K, White AA, Shimizu T. Meningitis mirage. J Hosp Med. 2025 Oct;20(10):1112-1117.
  6. Sakamoto T, Hirosawa T, Shimizu T. Recurrent Anemia Due To Mucosal Prolapse Syndrome. Eur J Case Rep Intern Med. 2025 Mar 21;12(4):005314.
  7. Kunitomo K, Harada Y, Tsuji T, Shimizu T. Positive Murphy’s Sign of Fitz-Hugh-Curtis Syndrome. Cureus. 2025 Feb 4;17(2):e78521.

 

【その他（英文）】

  1. Hirata R, Tago M, Takahashi H, Watari T, Shikino K, Sasaki Y, Shimizu T. A Questionnaire Study of Leadership in General Medicine: General Physicians in Japan are Facing Challenges in Education and Research [Response to Letter]. Int J Gen Med. 2025 Mar 2;18:1215-1216.

 

【原著・症例報告・その他（和文）】

  1. 原田侑典,綿貫聡, 青木拓也, 伊藤優, 居安綾子, 上原孝紀, 石丸裕康, 芦野朱, 山口章江. プライマリ・ケア現場における診断エクセレンスの実践を探る. 日本プライマリ・ケア連合学会誌. 2025年48巻4号p.141-144.
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